Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 1/20 | 0.56 |
| ▸ | DRD3 | P35462 | 4/20 | 0.55 |
| ▸ | HTR1A | P08908 | 3/20 | 0.55 |
| ▸ | HTR2A | P28223 | 3/20 | 0.55 |
| ▸ | HTR7 | P34969 | 3/20 | 0.55 |
| ▸ | DRD4 | P21917 | 3/20 | 0.55 |
| ▸ | KDM1A | O60341 | 1/20 | 0.51 |
| ▸ | MAOA | P21397 | 6/20 | 0.50 |
| ▸ | MAOB | P27338 | 6/20 | 0.50 |
| ▸ | DRD2 | P14416 | 4/20 | 0.50 |
| ▸ | HTR2C | P28335 | 2/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.50 |
| ▸ | KCNA5 | P22460 | 3/20 | 0.48 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11044734 | 0.88 | KCNA5 (0.63) | DRD3HTR2AKDM1ADRD2KCNA5 | |
| Hydrochloric Acid SCHEMBL11041972 | 0.87 | KCNA5 (0.61) | DRD3HTR2AKDM1ADRD2KCNA5 | |
| Hydrochloric Acid SCHEMBL11044917 | 0.82 | DRD2 (0.57) | DRD3HTR1AHTR2AHTR7DRD4 | |
| Hydrochloric Acid SCHEMBL11045592 | 0.81 | DRD2 (0.61) | DRD3HTR1AHTR2AHTR7DRD4 | |
| Hydrochloric Acid SCHEMBL11041142 | 0.81 | DRD2 (0.60) | DRD3HTR1AHTR2AHTR7DRD4 | |
| Hydrochloric Acid SCHEMBL11042505 | 0.80 | KCNA5 (0.60) | DRD3HTR2ADRD4MAOAMAOB | |
| Hydrochloric Acid SCHEMBL7346504 | 0.80 | KCNA5 (0.47) | DRD3DRD2KCNA5MEN1KMT2A | |
| SCHEMBL7344494 | 0.79 | GRIN2B (0.57) | GRIN2BDRD3HTR1AHTR2AHTR7 | |
| Hydrochloric Acid SCHEMBL11255645 | 0.79 | GRIN2B (0.57) | GRIN2BDRD3HTR1AHTR2AHTR7 | |
| SCHEMBL7288177 | 0.79 | GRIN2B (0.57) | GRIN2BDRD3HTR1AHTR2AHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4514401-A | CARDIOTONICS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1985-04-30 | — | — | US | disclosed |