Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 6/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ITGAV | P06756 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | TTR | P02766 | 1/20 | 0.37 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7342272 | 0.90 | ITGB3 (0.41) | ITGB3ITGA2BHTTLMNASMN1; SMN2 | |
| SCHEMBL7347469 | 0.89 | ITGB3 (0.40) | ITGB3ITGA2BHTTSMN1; SMN2L3MBTL1 | |
| SCHEMBL7341242 | 0.89 | MEN1 (0.42) | ITGB3ITGA2BALDH1A1HTTLMNA | |
| SCHEMBL7348081 | 0.89 | ITGB3 (0.43) | ITGB3ITGA2BHTTLMNASMN1; SMN2 | |
| SCHEMBL7346220 | 0.88 | HTT (0.39) | ITGB3ITGA2BALDH1A1HTTLMNA | |
| SCHEMBL7339858 | 0.86 | ITGB3 (0.41) | ITGB3ITGA2BALDH1A1HTTLMNA | |
| SCHEMBL7340238 | 0.84 | LMNA (0.46) | ITGB3ALDH1A1HTTLMNASMN1; SMN2 | |
| SCHEMBL7346981 | 0.83 | SMN1; SMN2 (0.39) | ITGB3ITGA2BALDH1A1HTTLMNA | |
| Propionic Acid SCHEMBL7337734 | 0.83 | LMNA (0.44) | ITGB3ALDH1A1HTTLMNASMN1; SMN2 | |
| SCHEMBL7345081 | 0.83 | ITGB3 (0.40) | ITGB3ITGA2BHTTLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0850221-A1 | META-GUANIDINE, UREA, THIOUREA OR AZACYCLIC AMINO BENZOIC ACID DERIVATIVES AS INTEGRIN ANTAGONISTS | G.D. SEARLE & CO. (US) | 1998-07-01 | — | — | EP | claimed |
| WO-1997008145-A1 | META-GUANIDINE, UREA, THIOUREA OR AZACYCLIC AMINO BENZOIC ACID DERIVATIVES AS INTEGRIN ANTAGONISTS | G.D. SEARLE & CO. (US) | 1997-03-06 | — | — | WO | claimed |