Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 8/20 | 0.55 |
| ▸ | RXRB | P28702 | 7/20 | 0.55 |
| ▸ | RXRG | P48443 | 5/20 | 0.55 |
| ▸ | MRGPRX4 | Q96LA9 | 5/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15871969 | 0.83 | CYP19A1 (0.50) | MRGPRX4SMN1; SMN2 | |
| SCHEMBL6861456 | 0.82 | KEAP1 (0.53) | RXRARXRBRXRGMRGPRX4 | |
| SCHEMBL6861660 | 0.82 | KEAP1 (0.50) | RXRARXRBRXRGMRGPRX4HPGD | |
| SCHEMBL6862284 | 0.81 | KEAP1 (0.49) | RXRARXRBRXRGMRGPRX4HPGD | |
| SCHEMBL6862227 | 0.81 | KEAP1 (0.49) | RXRARXRBRXRGMRGPRX4HPGD | |
| SCHEMBL6864044 | 0.80 | RXRA (0.51) | RXRARXRBRXRGMRGPRX4 | |
| SCHEMBL7338948 | 0.80 | CYP19A1 (0.53) | RXRARXRBRXRGMRGPRX4NPC1 | |
| SCHEMBL6856173 | 0.79 | RXRA (0.44) | RXRARXRBRXRGMRGPRX4HPGD | |
| SCHEMBL7339290 | 0.79 | RXRA (0.47) | RXRARXRBRXRGMRGPRX4HPGD | |
| SCHEMBL6862663 | 0.78 | KEAP1 (0.47) | RXRARXRBRXRGMRGPRX4HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832061-B1 | BENZAMIDE DERIVATIVES AND THEIR USE AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 2001-09-05 | — | — | EP | disclosed |
| US-6054457-A | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-04-25 | — | — | US | disclosed |
| EP-0832061-A1 | BENZAMIDE DERIVATIVES AND THEIR USE AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-04-01 | — | — | EP | disclosed |
| WO-1996041795-A1 | BENZAMIDE DERIVATIVES AND THEIR USE AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-12-27 | — | — | WO | disclosed |