Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 3/20 | 0.53 |
| ▸ | CTSS | P25774 | 5/20 | 0.53 |
| ▸ | CTSK | P43235 | 4/20 | 0.53 |
| ▸ | CTSB | P07858 | 2/20 | 0.50 |
| ▸ | CTSL | P07711 | 1/20 | 0.50 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.46 |
| ▸ | AKT1 | P31749 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | REN | P00797 | 2/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7346655 | 1.00 | ACE (0.53) | ACECTSSCTSKCTSBCTSL | |
| SCHEMBL10758814 | 0.87 | ACE (0.61) | ACECTSSCTSKCTSBCTSL | |
| SCHEMBL10758805 | 0.87 | ACE (0.61) | ACECTSSCTSKCTSBCTSL | |
| SCHEMBL7339869 | 0.82 | ACE (0.55) | ACECTSSCTSKCTSBCTSL | |
| SCHEMBL7339862 | 0.82 | ACE (0.55) | ACECTSSCTSKCTSBCTSL | |
| SCHEMBL3699838 | 0.81 | CTSS (0.54) | ACECTSSCTSKCTSBCTSL | |
| SCHEMBL3699836 | 0.81 | CTSS (0.54) | ACECTSSCTSKCTSBCTSL | |
| SCHEMBL7340534 | 0.81 | ACE (0.54) | ACECTSSCTSKCTSBCTSL | |
| SCHEMBL7340544 | 0.81 | ACE (0.54) | ACECTSSCTSKCTSBCTSL | |
| SCHEMBL8308836 | 0.80 | CTSS (0.70) | ACECTSSCTSKCTSBCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0603873-B1 | Aminoketone derivatives | MITSUBISHI CHEM CORP (JP) | 1998-04-15 | — | — | EP | disclosed |
| US-5424325-A | Inibitors of thiol protease and may be used as therapeutic agents for treating muscular dystrophy, cataracts, strokes | MITSUBISHI KASEI CORPORATION (JP) | 1995-06-13 | — | — | US | disclosed |
| EP-0603873-A1 | Aminoketone derivatives | Mitsubishi Chemical Corporation (JP) | 1994-06-29 | — | — | EP | disclosed |