Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.69 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | CPB1 | P15086 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | FOLH1 | Q04609 | 4/20 | 0.52 |
| ▸ | TGM2 | P21980 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | MME | P08473 | 1/20 | 0.51 |
| ▸ | ECE1 | P42892 | 1/20 | 0.51 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.50 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.50 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.48 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL127662 | 0.91 | HTT (0.82) | HTTLMNASMN1; SMN2CPB1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL7400993 | 0.90 | HTT (0.79) | HTTLMNASMN1; SMN2CPB1L3MBTL1 | |
| Glycolic Acid SCHEMBL148706 | 0.87 | HTT (0.75) | HTTLMNASMN1; SMN2CPB1L3MBTL1 | |
| SCHEMBL7514786 | 0.85 | HTT (0.73) | HTTLMNASMN1; SMN2CPB1L3MBTL1 | |
| Trifluoroacetic Acid SCHEMBL5050603 | 0.84 | HTT (0.53) | HTTLMNASMN1; SMN2L3MBTL1MEN1 | |
| Trifluoroacetic Acid SCHEMBL21925541 | 0.82 | LMNA (0.55) | HTTLMNASMN1; SMN2L3MBTL1MEN1 | |
| SCHEMBL16219550 | 0.82 | HTT (0.73) | HTTLMNASMN1; SMN2CPB1L3MBTL1 | |
| SCHEMBL7347005 | 0.82 | HTT (0.57) | HTTLMNASMN1; SMN2CPB1L3MBTL1 | |
| SCHEMBL319161 | 0.82 | HTT (1.00) | HTTLMNASMN1; SMN2L3MBTL1MEN1 | |
| SCHEMBL7510972 | 0.81 | HTT (0.67) | HTTLMNASMN1; SMN2CPB1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998043962-A1 | HETEROCYCLIC INTEGRIN INHIBITOR PRODRUGS | DU PONT PHARMACEUTICALS COMPANY (US) | 1998-10-08 | — | — | WO | disclosed |
| US-5721366-A | PHENYLAMIDINE DERIVATIVES | G. D. SEARLE & CO (US) | 1998-02-24 | — | — | US | disclosed |