SCHEMBL319161

SCHEMBL319161

O=C(O)CCCNC(=O)OCc1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 1.00
LMNA P02545 1/20 0.67
SMN1; SMN2 Q16637 1/20 0.67
TGM2 P21980 1/20 0.63
FOLH1 Q04609 6/20 0.63
KEAP1 Q14145 2/20 0.62
NFE2L2 Q16236 2/20 0.62
ATM Q13315 1/20 0.59
MEN1 O00255 1/20 0.58
KMT2A Q03164 1/20 0.58
L3MBTL1 Q9Y468 2/20 0.55
HDAC3 O15379 1/20 0.55
HDAC4 P56524 1/20 0.55
HDAC1 Q13547 1/20 0.55
HDAC7 Q8WUI4 1/20 0.55
HDAC2 Q92769 1/20 0.55
HDAC10 Q969S8 1/20 0.55
HDAC11 Q96DB2 1/20 0.55
HDAC8 Q9BY41 1/20 0.55
HDAC6 Q9UBN7 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL879577 0.95 HTT (0.91) HTTLMNASMN1; SMN2TGM2FOLH1
SCHEMBL7820797 0.94 HTT (0.89) HTTLMNASMN1; SMN2TGM2FOLH1
SCHEMBL4858734 0.94 HTT (0.88) HTTLMNASMN1; SMN2TGM2FOLH1
SCHEMBL3287016 0.94 HTT (0.88) HTTLMNASMN1; SMN2TGM2FOLH1
SCHEMBL3694316 0.94 HTT (0.88) HTTLMNASMN1; SMN2TGM2FOLH1
SCHEMBL4857273 0.94 HTT (0.88) HTTLMNASMN1; SMN2TGM2FOLH1
SCHEMBL2876850 0.94 HTT (0.88) HTTLMNASMN1; SMN2TGM2FOLH1
SCHEMBL125577 0.94 HTT (0.88) HTTLMNASMN1; SMN2TGM2FOLH1
SCHEMBL2875581 0.94 HTT (0.88) HTTLMNASMN1; SMN2TGM2FOLH1
SCHEMBL3693087 0.94 HTT (0.88) HTTLMNASMN1; SMN2TGM2FOLH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 487 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115716856-A Method for synthesizing aminoglycoside antibiotic arbekacin 山东厚德精诚药业有限公司 2023-02-28 CN claimed
US-7728167-B2 Process for the preparation of enantiomerically enriched amino acids DEGUSSA AG (DE) 2010-06-01 US claimed
EP-2123253-A1 WRINKLING-PREVENTING AND -MODIFYING AGENT Shiseido Company, Ltd. (JP) 2009-11-25 EP claimed
US-20260108619-A1 CONJUGATION LINKERS, CELL BINDING MOLECULE-DRUG CONJUGATES CONTAINING THE LINKERS, METHODS OF MAKING AND USES SUCH CONJUGATES WITH THE LINKERS HANGZHOU DAC BIOTECH CO., LTD. (CN) 2026-04-23 US disclosed
US-20260091081-A1 A FORMULATION OF A CONJUGATE OF A TUBULYSIN ANALOG TO A CELL-BINDING MOLECULE HANGZHOU DAC BIOTECH CO., LTD (CN) 2026-04-02 US disclosed
US-12576124-B2 Formulation of a conjugate of a tubulysin analog to a cell-binding molecule HANGZHOU DAC BIOTECH CO., LTD (CN) 2026-03-17 US disclosed
WO-2026043829-A1 CHROMANE CYCLIC AMIDINE MONOBACTAM COMPOUNDS FOR THE TREATMENT OF BACTERIAL INFECTIONS MERCK SHARP & DOHME LLC (US) 2026-02-26 WO disclosed
US-20260041686-A1 CYTOTOXICITY TARGETING CHIMERAS FOR CCR2-EXPRESSING CELLS GLAXOSMITHKLINE IP DEV LTD (GB) 2026-02-12 US disclosed
US-12521393-B2 Cytotoxicity targeting chimeras for CCR2-expressing cells GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) 2026-01-13 US disclosed
US-20260009029-A1 COMPOUND FOR INHIBITING EXPRESSION OF LPA GENE, PHARMACEUTICAL COMPOSITION AND USE THEREOF RIGERNA THERAPEUTICS SUZHOU CO LTD (CN) 2026-01-08 US disclosed
US-20260009030-A1 COMPOUND FOR INHIBITING AGT GENE EXPRESSION, AND PHARMACEUTICAL COMPOSITION AND USE THEREOF RIGERNA THERAPEUTICS SUZHOU CO LTD (CN) 2026-01-08 US disclosed
US-4515717-A INTERMEDIATES FOR 6-UNSUBSTITUTED PENICILLIN ANTIOBIOTICS CIBA GEIGY CORPORATION (US) 1985-05-07 US disclosed
US-4500457-A TREATING AN ACYLOXYAZETIDINONE WITH MERCAPTO COMPOUND, GLYOYLIC ESTER, HALOGENATION AGENT, AND PHOSPHINE COMPOUNT THEN CYCLIZATION CIBA-GEIGY CORPORATION (US) 1985-02-19 US disclosed
US-4476229-A QUANTITATIVE ANALYSIS OF LIGANDS IN BIOLOGICAL FLUIDS ABBOTT LABORATORIES (US) 1984-10-09 US disclosed
US-4472379-A ANTILEUKEMIA AGENTS SUAMI T (JP) 1984-09-18 US disclosed
EP-0108399-A2 Substituted carboxyfluoresceins ABBOTT LABORATORIES (US) 1984-05-16 EP disclosed
US-4447360-A Intermediates for thia-aza compounds with a β-lactam ring CIBA-GEIGY CORPORATION (US) 1984-05-08 US disclosed
US-4331676-A 2-PENEM COMPOUNDS UNSUBSTITUTED IN THE 6 POSITION CIBA-GEIGY CORPORATION (US) 1982-05-25 US disclosed
US-4221706-A B-ALANYL OR G-AMINOBUTYRYL-PROLYL-ARGINYL-P-NITROANILIDE, FOR QUANTITATIVE MEASUREMENT OF PROTEOLYTIC ENZYMES ABBOTT LABORATORIES (US) 1980-09-09 US disclosed
US-4218404-A HYPOGLYCEMIC AGENTS CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT. (HU) 1980-08-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12576124-B2 Formulation of a conjugate of a tubulysin analog to a cell-binding molecule CD4, TAP1, MCTS1 HTT 1768/4885LMNA 2109/4885SMN1; SMN2 1758/4885
US-20260041686-A1 CYTOTOXICITY TARGETING CHIMERAS FOR CCR2-EXPRESSING CELLS CCR2, CCR1, CCRL2 HTT 2256/4885LMNA 4546/4885SMN1; SMN2 1993/4885
US-20260091081-A1 A FORMULATION OF A CONJUGATE OF A TUBULYSIN ANALOG TO A CELL-BINDING MOLECULE CD4, MALT1, LY6K HTT 2917/4885LMNA 2507/4885SMN1; SMN2 3725/4885
US-20260009030-A1 COMPOUND FOR INHIBITING AGT GENE EXPRESSION, AND PHARMACEUTICAL COMPOSITION AND USE THEREOF AGTR1, AGT, AGTR2 HTT 1981/4885LMNA 488/4885SMN1; SMN2 1612/4885
US-20260009029-A1 COMPOUND FOR INHIBITING EXPRESSION OF LPA GENE, PHARMACEUTICAL COMPOSITION AND USE THEREOF LPAR6, LPAR2, LPAR1 HTT 2902/4885LMNA 332/4885SMN1; SMN2 3145/4885
US-20260108619-A1 CONJUGATION LINKERS, CELL BINDING MOLECULE-DRUG CONJUGATES CONTAINING THE LINKERS, METHODS OF MAKING AND USES SUCH CONJUGATES WITH THE LINKERS DCLRE1A, CCR3, CCR8 HTT 3952/4885LMNA 852/4885SMN1; SMN2 4051/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.