Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR2 | P50052 | 1/20 | 0.55 |
| ▸ | MME | P08473 | 1/20 | 0.53 |
| ▸ | ECE1 | P42892 | 1/20 | 0.53 |
| ▸ | ITGB2 | P05107 | 3/20 | 0.48 |
| ▸ | ICAM1 | P05362 | 3/20 | 0.48 |
| ▸ | ITGAL | P20701 | 3/20 | 0.48 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.48 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | REN | P00797 | 5/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7322345 | 0.91 | MME (0.59) | AGTR2MMEECE1ITGB2ICAM1 | |
| SCHEMBL7307725 | 0.91 | MME (0.59) | AGTR2MMEECE1ITGB2ICAM1 | |
| SCHEMBL7313805 | 0.90 | MME (0.55) | AGTR2MMEECE1ITGB2ICAM1 | |
| SCHEMBL7314274 | 0.87 | MRGPRX4 (0.56) | AGTR2MMEECE1ITGB2ICAM1 | |
| SCHEMBL7314528 | 0.87 | MRGPRX4 (0.56) | AGTR2MMEECE1ITGB2ICAM1 | |
| SCHEMBL7317366 | 0.86 | CA2 (0.56) | AGTR2MMEECE1ITGB2ICAM1 | |
| SCHEMBL7347192 | 0.83 | KMO (0.43) | MME | |
| SCHEMBL7347170 | 0.83 | KMO (0.43) | MME | |
| SCHEMBL7347160 | 0.83 | KMO (0.43) | MME | |
| SCHEMBL7311278 | 0.83 | MME (0.53) | AGTR2MMEECE1ITGB2ICAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5459131-A | Renin inhibitors | AMERICAN CYANAMID COMPANY (US) | 1995-10-17 | — | — | US | disclosed |