Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.46 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.46 |
| ▸ | PPIA | P62937 | 2/20 | 0.44 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 2/20 | 0.39 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16361430 | 0.82 | HDAC3 (0.50) | KMT2AMEN1LMNAPPIABCHE | |
| SCHEMBL8749961 | 0.76 | PGR (0.48) | KMT2AMEN1LMNAHSD17B1HSD17B2 | |
| SCHEMBL14492674 | 0.73 | HTR7 (0.46) | KMT2AMEN1LMNAHSD17B1HSD17B2 | |
| SCHEMBL30431051 | 0.73 | HTR7 (0.46) | KMT2AMEN1LMNAHSD17B1HSD17B2 | |
| Hydrochloric Acid SCHEMBL4632310 | 0.72 | ELANE (0.44) | KMT2AMEN1LMNAHSD17B1HSD17B2 | |
| SCHEMBL16230462 | 0.72 | HTR7 (0.47) | KMT2AMEN1LMNAHSD17B1HSD17B2 | |
| SCHEMBL9449414 | 0.71 | HRH3 (0.46) | KMT2AMEN1LMNAHSD17B1HSD17B2 | |
| Hydrochloric Acid SCHEMBL5355296 | 0.70 | ELANE (0.42) | KMT2AMEN1LMNAHSD17B1HSD17B2 | |
| SCHEMBL9449539 | 0.70 | HDAC3 (0.44) | KMT2AMEN1LMNAHSD17B1HSD17B2 | |
| SCHEMBL18760067 | 0.70 | HDAC3 (0.44) | KMT2AMEN1LMNAHSD17B1HSD17B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5112846-A | Nonsteroidal antiinflammatory agents | WARNER-LAMBERT COMPANY (US) | 1992-05-12 | — | — | US | disclosed |
| US-5075330-A | N-hydroxyamide, N-hydroxythioamide, N-hydroxyurea, and N-hydroxythiourea derivatives of selected NSAIDS as antiinflammatory agents | WARNER-LAMBERT CO. (US) | 1991-12-24 | — | — | US | disclosed |
| US-4981865-A | N-hydroxyamide, N-hydroxythioamide, hydroxyurea, and N-hydroxythiourea derivatives of selected nsaids as antiinflammatory agents | WARNER-LAMBERT CO. (US) | 1991-01-01 | — | — | US | disclosed |