Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 1/20 | 0.55 |
| ▸ | CTSS | P25774 | 1/20 | 0.55 |
| ▸ | CTSK | P43235 | 1/20 | 0.55 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | PSEN1 | P49768 | 3/20 | 0.45 |
| ▸ | PSEN2 | P49810 | 3/20 | 0.45 |
| ▸ | APH1B | Q8WW43 | 3/20 | 0.45 |
| ▸ | NCSTN | Q92542 | 3/20 | 0.45 |
| ▸ | APH1A | Q96BI3 | 3/20 | 0.45 |
| ▸ | PSENEN | Q9NZ42 | 3/20 | 0.45 |
| ▸ | APP | P05067 | 1/20 | 0.45 |
| ▸ | FCER2 | P06734 | 2/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.43 |
| ▸ | REN | P00797 | 3/20 | 0.42 |
| ▸ | ACE | P12821 | 2/20 | 0.42 |
| ▸ | MME | P08473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9439828 | 0.84 | CTSB (0.54) | CTSBCTSSCTSKKLK5PTPN1 | |
| SCHEMBL7345250 | 0.84 | CTSB (0.54) | CTSBCTSSCTSKKLK5PTPN1 | |
| SCHEMBL9439832 | 0.84 | CTSB (0.54) | CTSBCTSSCTSKKLK5PTPN1 | |
| SCHEMBL9439843 | 0.84 | CTSB (0.54) | CTSBCTSSCTSKKLK5PTPN1 | |
| Acetone SCHEMBL7364225 | 0.78 | CTSS (0.55) | CTSBCTSSCTSKKLK5PTPN1 | |
| SCHEMBL11028734 | 0.78 | CTSS (0.62) | CTSBCTSSCTSKPTPN1FCER2 | |
| SCHEMBL739925 | 0.77 | CTSS (0.62) | CTSBCTSSCTSKKLK5PTPN1 | |
| SCHEMBL739924 | 0.77 | CTSS (0.62) | CTSBCTSSCTSKKLK5PTPN1 | |
| SCHEMBL14332332 | 0.77 | CTSS (0.62) | CTSBCTSSCTSKKLK5PTPN1 | |
| SCHEMBL30753701 | 0.77 | CTSS (0.62) | CTSBCTSSCTSKKLK5PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992013545-A1 | ENDOTHELIN CONVERTING ENZYME INHIBITORS | ABBOTT LABORATORIES (US) | 1992-08-20 | — | — | WO | disclosed |