Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 12/20 | 0.46 |
| ▸ | CCR5 | P51681 | 2/20 | 0.40 |
| ▸ | HTR2A | P28223 | 2/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.37 |
| ▸ | NPY1R | P25929 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7348708 | 0.92 | CACNA1B (0.46) | CACNA1BCCR5HTR2A | |
| SCHEMBL7355063 | 0.92 | CACNA1B (0.55) | CACNA1BCCR5 | |
| SCHEMBL7357987 | 0.90 | CCR5 (0.38) | CACNA1BCCR5SIGMAR1 | |
| SCHEMBL7359587 | 0.85 | CACNA1B (0.46) | CACNA1BHTR2ASIGMAR1 | |
| SCHEMBL7351179 | 0.84 | CACNA1B (0.40) | CACNA1BCCR5HTR2A | |
| SCHEMBL7350731 | 0.83 | CACNA1B (0.42) | CACNA1BHTR2A | |
| SCHEMBL7043607 | 0.82 | CACNA1B (0.45) | CACNA1BCCR5HTR2ASIGMAR1 | |
| SCHEMBL7043604 | 0.82 | CACNA1B (0.45) | CACNA1BCCR5HTR2ASIGMAR1 | |
| SCHEMBL7043507 | 0.82 | CACNA1B (0.49) | CACNA1BHTR2ASIGMAR1 | |
| SCHEMBL7043502 | 0.82 | CACNA1B (0.49) | CACNA1BHTR2ASIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999007689-A1 | ANILINE DERIVATIVES AS CALCIUM CHANNEL BLOCKERS | WARNER-LAMBERT COMPANY (US) | 1999-02-18 | — | — | WO | claimed |