Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 13/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7354530 | 0.92 | CACNA1B (0.46) | CACNA1BHRH3CYP2D6HTR2A | |
| SCHEMBL7355987 | 0.92 | CACNA1B (0.55) | CACNA1BHRH3LMNAGAARAB9A | |
| SCHEMBL7357693 | 0.91 | CHIT1 (0.38) | CACNA1BSIGMAR1 | |
| SCHEMBL7043502 | 0.87 | CACNA1B (0.49) | CACNA1BSIGMAR1CYP2D6HTR2A | |
| SCHEMBL7043507 | 0.87 | CACNA1B (0.49) | CACNA1BSIGMAR1CYP2D6HTR2A | |
| SCHEMBL7354424 | 0.87 | CACNA1B (0.57) | CACNA1BSIGMAR1HRH3CYP2D6 | |
| SCHEMBL7353642 | 0.86 | CHIT1 (0.37) | CACNA1B | |
| SCHEMBL7347443 | 0.85 | CACNA1B (0.46) | CACNA1BSIGMAR1HTR2A | |
| SCHEMBL7355433 | 0.84 | CACNA1B (0.40) | CACNA1BSIGMAR1CYP2D6 | |
| SCHEMBL7355754 | 0.84 | CACNA1B (0.54) | CACNA1BSIGMAR1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999007689-A1 | ANILINE DERIVATIVES AS CALCIUM CHANNEL BLOCKERS | WARNER-LAMBERT COMPANY (US) | 1999-02-18 | — | — | WO | claimed |
| WO-1999007689-A1 | ANILINE DERIVATIVES AS CALCIUM CHANNEL BLOCKERS | WARNER-LAMBERT COMPANY (US) | 1999-02-18 | — | — | WO | disclosed |