Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.55 |
| ▸ | IDO1 | P14902 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | AKT1 | P31749 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CTSS | P25774 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7951856 | 0.91 | SYK (0.60) | SYKIDO1SMN1; SMN2CA12CA1 | |
| SCHEMBL2321117 | 0.88 | LMNA (0.56) | SMN1; SMN2CA12CA1NPC1RAB9A | |
| SCHEMBL421286 | 0.83 | SYK (0.61) | SYKIDO1SMN1; SMN2CA12CA1 | |
| SCHEMBL27449206 | 0.82 | SYK (0.52) | SYKIDO1SMN1; SMN2CA12CA1 | |
| SCHEMBL18620840 | 0.82 | ALDH1A1 (0.51) | SMN1; SMN2CA12CA1NPC1RAB9A | |
| SCHEMBL27536768 | 0.82 | ALDH1A1 (0.48) | RAB9AALDH1A1PPARAMAPT | |
| SCHEMBL19972926 | 0.79 | SYK (0.64) | SYKIDO1SMN1; SMN2CA12CA1 | |
| SCHEMBL15202883 | 0.79 | SYK (0.64) | SYKIDO1SMN1; SMN2MAPTLMNA | |
| SCHEMBL25054127 | 0.79 | SYK (0.55) | SYKIDO1MAPTMEN1KMT2A | |
| SCHEMBL8269064 | 0.79 | SYK (0.52) | SYKMAPTMEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1007544-A1 | SERINE PROTEASE INHIBITORS | Akzo Nobel N.V. (NL) | 2000-06-14 | — | — | EP | disclosed |
| US-6034067-A | ANTICOAGULANTS | AKZO NOBEL, N.V. (NL) | 2000-03-07 | — | — | US | disclosed |
| WO-1997030073-A1 | SERINE PROTEASE INHIBITORS | AKZO NOBEL N.V. (NL) | 1997-08-21 | — | — | WO | disclosed |