Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 2/20 | 0.46 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.41 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.41 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 4/20 | 0.40 |
| ▸ | MMP3 | P08254 | 2/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | NPY4R | P50391 | 6/20 | 0.39 |
| ▸ | NPY1R | P25929 | 4/20 | 0.39 |
| ▸ | NPY2R | P49146 | 3/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.39 |
| ▸ | MME | P08473 | 1/20 | 0.39 |
| ▸ | ACE | P12821 | 1/20 | 0.39 |
| ▸ | CPA1 | P15085 | 1/20 | 0.39 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.39 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.38 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.38 |
| ▸ | LNPEP | Q9UIQ6 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7348068 | 0.89 | PSMB5 (0.51) | CACNA1BPSMB5PSMB1PSMB2MMP1 | |
| SCHEMBL7337467 | 0.86 | CACNA1B (0.47) | CACNA1BPSMB5MMP1MMP3MMP2 | |
| SCHEMBL7337635 | 0.85 | CACNA1B (0.41) | CACNA1BPSMB5PSMB1PSMB2MMP1 | |
| SCHEMBL7343134 | 0.84 | MMP1 (0.52) | CACNA1BPSMB5MMP1MMP3MMP2 | |
| SCHEMBL7344639 | 0.84 | CACNA1B (0.45) | CACNA1BPSMB5PSMB1PSMB2MMP1 | |
| SCHEMBL7338188 | 0.81 | KMT2A (0.44) | CACNA1BPSMB5PSMB1PSMB2MMP1 | |
| SCHEMBL7340728 | 0.81 | CACNA1B (0.48) | CACNA1BMMP1MMP3MMP2MME | |
| SCHEMBL7338606 | 0.81 | CACNA1B (0.42) | CACNA1BMMP1MMP3MMP2NPY4R | |
| SCHEMBL7337048 | 0.81 | CACNA1B (0.48) | CACNA1BPSMB5MMP1MMP3MMP2 | |
| SCHEMBL7344645 | 0.80 | MMP1 (0.48) | CACNA1BPSMB5MMP1MMP3MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6423689-B1 | Peptidyl calcium channel blockers | WARNER-LAMBERT COMPANY | 2002-07-23 | — | — | US | claimed |
| US-6423689-B1 | Peptidyl calcium channel blockers | WARNER-LAMBERT COMPANY | 2002-07-23 | — | — | US | disclosed |