Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 2/20 | 0.48 |
| ▸ | MMP2 | P08253 | 10/20 | 0.47 |
| ▸ | MMP1 | P03956 | 9/20 | 0.47 |
| ▸ | MMP3 | P08254 | 8/20 | 0.47 |
| ▸ | MMP8 | P22894 | 5/20 | 0.44 |
| ▸ | MME | P08473 | 1/20 | 0.44 |
| ▸ | ACE | P12821 | 1/20 | 0.44 |
| ▸ | CPA1 | P15085 | 1/20 | 0.44 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 4/20 | 0.44 |
| ▸ | FCER2 | P06734 | 3/20 | 0.43 |
| ▸ | MMP7 | P09237 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7348068 | 0.88 | PSMB5 (0.51) | CACNA1BMMP2MMP1MMP3MMP8 | |
| SCHEMBL7343134 | 0.88 | MMP1 (0.52) | CACNA1BMMP2MMP1MMP3MMP8 | |
| SCHEMBL7337048 | 0.85 | CACNA1B (0.48) | CACNA1BMMP2MMP1MMP3MME | |
| SCHEMBL7339998 | 0.84 | CACNA1B (0.44) | CACNA1BMMP2MMP1MMP3 | |
| SCHEMBL7344645 | 0.83 | MMP1 (0.48) | CACNA1BMMP2MMP1MMP3MMP8 | |
| SCHEMBL7348626 | 0.83 | MMP1 (0.43) | CACNA1BMMP2MMP1MMP3 | |
| SCHEMBL7341162 | 0.82 | PTPN1 (0.47) | CACNA1BMMP2MMP1MMP3MMP8 | |
| SCHEMBL7338162 | 0.82 | MME (0.56) | CACNA1BMMP8MMEACECPA1 | |
| SCHEMBL7347666 | 0.81 | CACNA1B (0.46) | CACNA1BMMP2MMP1MMP3MME | |
| SCHEMBL20815883 | 0.80 | LTA4H (0.54) | MMP2MMP1MMP3MMEFCER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6423689-B1 | Peptidyl calcium channel blockers | WARNER-LAMBERT COMPANY | 2002-07-23 | — | — | US | claimed |
| US-6423689-B1 | Peptidyl calcium channel blockers | WARNER-LAMBERT COMPANY | 2002-07-23 | — | — | US | disclosed |