Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.40 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.35 |
| ▸ | TYMS | P04818 | 1/20 | 0.35 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.35 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.35 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7345932 | 0.92 | CES1 (0.40) | ALDH1A1HSD17B10KDM4EHPGDNOTUM | |
| SCHEMBL7336750 | 0.86 | CYP1A2 (0.36) | ALDH1A1KDM4EHPGDMAOAMAPT | |
| SCHEMBL7338904 | 0.82 | KDM4E (0.39) | ALDH1A1HSD17B10KDM4EHPGDCYP2A6 | |
| SCHEMBL7345733 | 0.80 | CYP2A6 (0.46) | ALDH1A1HSD17B10KDM4EHPGDCYP2A6 | |
| SCHEMBL7339006 | 0.79 | NOTUM (0.44) | ALDH1A1HSD17B10KDM4EHPGDNOTUM | |
| SCHEMBL7342355 | 0.78 | CES1 (0.40) | ALDH1A1HSD17B10KDM4EHPGDNOTUM | |
| Hydrochloric Acid SCHEMBL7337010 | 0.77 | CES1 (0.39) | ALDH1A1HSD17B10KDM4EHPGDNOTUM | |
| SCHEMBL11072613 | 0.75 | MEN1 (0.37) | ALDH1A1MAOBNOTUMALOX15MIF | |
| SCHEMBL11067060 | 0.75 | MAOA (0.41) | ALDH1A1HSD17B10KDM4EHPGDMAOA | |
| SCHEMBL7340881 | 0.74 | KDM4E (0.54) | ALDH1A1HSD17B10KDM4EHPGDNOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4511569-A | Tricyclic lactams and derivatives useful in increasing cardiac contractility | SCHERING CORPORATION (US) | 1985-04-16 | — | — | US | disclosed |