Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 6/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.43 |
| ▸ | F2 | P00734 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | F7 | P08709 | 2/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.37 |
| ▸ | CASP6 | P55212 | 1/20 | 0.37 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MDM4 | O15151 | 1/20 | 0.36 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.36 |
| ▸ | ITGAV | P06756 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9294970 | 0.86 | ITGB3 (0.46) | ITGB3ITGA2BF2TDP1 | |
| SCHEMBL7326730 | 0.83 | ITGB3 (0.41) | ITGB3ITGA2BF2TDP1F7 | |
| Trifluoroacetic Acid SCHEMBL7323357 | 0.79 | ITGB1 (0.40) | ITGB3ITGA2BF7ITGB1 | |
| SCHEMBL7345426 | 0.75 | ITGB3 (0.41) | ITGB3ITGA2BF10 | |
| SCHEMBL9296637 | 0.73 | ITGB3 (0.46) | ITGB3ITGA2B | |
| SCHEMBL9294657 | 0.72 | ITGB3 (0.43) | ITGB3ALDH1A1SMN1; SMN2MDM4ITGB1 | |
| SCHEMBL9295158 | 0.71 | ITGB3 (0.43) | ITGB3ITGA2BHDAC1HDAC6MDM4 | |
| SCHEMBL7317973 | 0.70 | ITGB3 (0.45) | ITGB3ITGA2B | |
| SCHEMBL7322874 | 0.69 | ITGB3 (0.47) | ITGB3ITGA2BF2F7F10 | |
| SCHEMBL6779388 | 0.69 | ITGB3 (0.55) | ITGB3ITGA2BITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0570507-A4 | ANTI-AGGREGATORY PEPTIDES CONTAINING AN AROMATIC ESTER OR AMIDE | SMITHKLINE BEECHAM CORP (US) | 1994-09-21 | — | — | EP | claimed |
| EP-0570507-A1 | ANTI-AGGREGATORY PEPTIDES CONTAINING AN AROMATIC ESTER OR AMIDE | SMITHKLINE BEECHAM CORPORATION (US) | 1993-11-24 | — | — | EP | claimed |
| WO-1992013552-A1 | ANTI-AGGREGATORY PEPTIDES CONTAINING AN AROMATIC ESTER OR AMIDE | SMITHKLINE BEECHAM CORPORATION (US) | 1992-08-20 | — | — | WO | claimed |
| EP-0570507-A4 | ANTI-AGGREGATORY PEPTIDES CONTAINING AN AROMATIC ESTER OR AMIDE | SMITHKLINE BEECHAM CORP (US) | 1994-09-21 | — | — | EP | disclosed |
| EP-0570507-A1 | ANTI-AGGREGATORY PEPTIDES CONTAINING AN AROMATIC ESTER OR AMIDE | SMITHKLINE BEECHAM CORPORATION (US) | 1993-11-24 | — | — | EP | disclosed |
| WO-1992013552-A1 | ANTI-AGGREGATORY PEPTIDES CONTAINING AN AROMATIC ESTER OR AMIDE | SMITHKLINE BEECHAM CORPORATION (US) | 1992-08-20 | — | — | WO | disclosed |