Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 6/20 | 0.43 |
| ▸ | ITGB1 | P05556 | 6/20 | 0.43 |
| ▸ | ITGAV | P06756 | 6/20 | 0.43 |
| ▸ | ITGA5 | P08648 | 6/20 | 0.43 |
| ▸ | MDM4 | O15151 | 3/20 | 0.43 |
| ▸ | MDM2 | Q00987 | 5/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.40 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.40 |
| ▸ | PTPRA | P18433 | 1/20 | 0.40 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.40 |
| ▸ | CTSC | P53634 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7355857 | 0.81 | ITGB3 (0.45) | ITGB3ITGB1ITGAVITGA5MDM4 | |
| SCHEMBL2377610 | 0.78 | CCKBR (0.45) | ITGB3ITGB1ITGAVITGA5MDM4 | |
| SCHEMBL7346263 | 0.77 | ITGB3 (0.46) | ITGB3ITGB1ITGAVITGA5MDM4 | |
| SCHEMBL7699974 | 0.76 | ALDH1A1 (0.57) | ALDH1A1CA1GAASMN1; SMN2 | |
| SCHEMBL8013551 | 0.75 | ALDH1A1 (0.49) | ALDH1A1CA1GAASMN1; SMN2 | |
| SCHEMBL27450014 | 0.75 | MME (0.56) | ITGB3CTSC | |
| SCHEMBL29574387 | 0.75 | MME (0.56) | ITGB3CTSC | |
| SCHEMBL27450013 | 0.75 | MME (0.56) | ITGB3CTSC | |
| SCHEMBL9295158 | 0.75 | ITGB3 (0.43) | ITGB3ITGB1ITGAVITGA5MDM4 | |
| SCHEMBL7352151 | 0.74 | ITGB3 (0.44) | ITGB3ITGB1ITGAVITGA5MDM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0570507-A4 | ANTI-AGGREGATORY PEPTIDES CONTAINING AN AROMATIC ESTER OR AMIDE | SMITHKLINE BEECHAM CORP (US) | 1994-09-21 | — | — | EP | disclosed |
| EP-0570507-A1 | ANTI-AGGREGATORY PEPTIDES CONTAINING AN AROMATIC ESTER OR AMIDE | SMITHKLINE BEECHAM CORPORATION (US) | 1993-11-24 | — | — | EP | disclosed |