SCHEMBL7348194

SCHEMBL7348194

COc1cc(Cc2ccccc2-c2ccc(OCCCC(=O)O)cc2)ccc1CN1CCCC1=O

nearest known ligand 0.45

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
FFAR4 Q5NUL3 7/20 0.45
BDKRB1 P46663 1/20 0.44
FFAR1 O14842 2/20 0.43
ACHE P22303 3/20 0.42
CD274 Q9NZQ7 5/20 0.42
PPARG P37231 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7985970 0.84 F2 (0.53)
SCHEMBL6968891 0.80 MCHR1 (0.48) CD274
SCHEMBL6966769 0.79 F2 (0.58)
SCHEMBL7348546 0.78 F2 (0.57) CD274
SCHEMBL7511215 0.77 LTA4H (0.43) FFAR4
SCHEMBL7446083 0.75 F2 (0.60) CD274
SCHEMBL7378181 0.75 SMN1; SMN2 (0.45) CD274
SCHEMBL7349015 0.73 CD274 (0.47) CD274
SCHEMBL7987881 0.71 F2 (0.67)
SCHEMBL7352161 0.71 F2 (0.56) CD274

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0993300-A4 ANTITHROMBOTIC AGENTS LILLY CO ELI (US) 2002-07-31 EP disclosed
EP-0993300-A1 ANTITHROMBOTIC AGENTS ELI LILLY AND COMPANY (US) 2000-04-19 EP disclosed
WO-1998048798-A1 ANTITHROMBOTIC AGENTS ELI LILLY AND COMPANY (US) 1998-11-05 WO disclosed