Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.47 |
| ▸ | F2 | P00734 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | NPY1R | P25929 | 1/20 | 0.43 |
| ▸ | MET | P08581 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7352161 | 0.90 | F2 (0.56) | CD274F2SMN1; SMN2 | |
| SCHEMBL7447052 | 0.87 | CD274 (0.55) | CD274F2MEN1KMT2AHRH3 | |
| SCHEMBL7442536 | 0.86 | CD274 (0.49) | CD274F2MEN1KMT2AHRH3 | |
| SCHEMBL7972046 | 0.85 | F2 (0.66) | F2 | |
| SCHEMBL7355874 | 0.84 | CD274 (0.54) | CD274F2MEN1KMT2AHRH3 | |
| SCHEMBL7348546 | 0.84 | F2 (0.57) | CD274F2MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7452057 | 0.83 | HRH3 (0.54) | CD274F2MEN1KMT2AHRH3 | |
| SCHEMBL7348647 | 0.83 | F2 (0.53) | CD274F2MEN1KMT2AHRH3 | |
| SCHEMBL7354252 | 0.81 | MEN1 (0.47) | CD274F2MEN1KMT2AHRH3 | |
| SCHEMBL6965070 | 0.80 | LTA4H (0.53) | F2HRH3NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0993300-A4 | ANTITHROMBOTIC AGENTS | LILLY CO ELI (US) | 2002-07-31 | — | — | EP | disclosed |
| EP-0993300-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 2000-04-19 | — | — | EP | disclosed |
| WO-1998048798-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 1998-11-05 | — | — | WO | disclosed |