Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 12/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.60 |
| ▸ | PKM | P14618 | 5/20 | 0.60 |
| ▸ | MEN1 | O00255 | 5/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 5/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.58 |
| ▸ | RAB9A | P51151 | 3/20 | 0.58 |
| ▸ | RAD52 | P43351 | 1/20 | 0.58 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.51 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.51 |
| ▸ | APEX1 | P27695 | 2/20 | 0.50 |
| ▸ | GLA | P06280 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | GFER | P55789 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7348235 | 0.88 | MAPT (0.53) | MAPTALDH1A1KDM4EPKMMEN1 | |
| SCHEMBL10891261 | 0.86 | MAPT (0.59) | MAPTALDH1A1KDM4EPKMMEN1 | |
| SCHEMBL18826597 | 0.85 | MAPT (0.82) | MAPTALDH1A1KDM4EPKMMEN1 | |
| SCHEMBL10891264 | 0.84 | RAD52 (0.62) | MAPTALDH1A1KDM4EPKMMEN1 | |
| SCHEMBL16443968 | 0.82 | MAPT (0.61) | MAPTALDH1A1KDM4EPKMMEN1 | |
| SCHEMBL3214301 | 0.81 | TDP1 (0.67) | ALDH1A1TDP1RAB9AAPEX1NPC1 | |
| SCHEMBL38661086 | 0.81 | IDO1 (0.59) | MAPTALDH1A1APEX1NPSR1 | |
| SCHEMBL7357590 | 0.80 | HSD17B10 (0.67) | MAPTALDH1A1KDM4EPKMMEN1 | |
| SCHEMBL520978 | 0.80 | RAD52 (0.69) | MAPTALDH1A1KDM4EPKMMEN1 | |
| SCHEMBL4069591 | 0.78 | PIN1 (0.63) | MAPTALDH1A1GRIN1GRIN2BAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5741804-A | Substituted benzimazoles which inhibit platelet aggrecation | SMITHKLINE BEECHAM CORPORATION (US) | 1998-04-21 | — | — | US | disclosed |
| EP-0672034-A4 | BENZIMIDAZOLE COMPOUNDS WHICH INHIBIT PLATELET AGGREGATION. | SMITHKLINE BEECHAM CORP (US) | 1996-09-25 | — | — | EP | disclosed |
| EP-0672034-A1 | BENZIMIDAZOLE COMPOUNDS WHICH INHIBIT PLATELET AGGREGATION | SMITHKLINE BEECHAM CORPORATION (US) | 1995-09-20 | — | — | EP | disclosed |
| WO-1994012478-A1 | BENZIMIDAZOLE COMPOUNDS WHICH INHIBIT PLATELET AGGREGATION | SMITHKLINE BEECHAM CORPORATION (US) | 1994-06-09 | — | — | WO | disclosed |