Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 13/20 | 0.68 |
| ▸ | MMP13 | P45452 | 13/20 | 0.68 |
| ▸ | MMP9 | P14780 | 12/20 | 0.68 |
| ▸ | MMP8 | P22894 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7622859 | 0.93 | MMP13 (0.71) | MMP1MMP13MMP9 | |
| SCHEMBL7352349 | 0.86 | MMP13 (0.73) | MMP1MMP13MMP9 | |
| SCHEMBL6928874 | 0.81 | MMP1 (1.00) | MMP1MMP13MMP9 | |
| SCHEMBL27478782 | 0.81 | MMP13 (0.78) | MMP1MMP13MMP9MMP8 | |
| SCHEMBL6928884 | 0.80 | MMP1 (0.56) | MMP1MMP13MMP9 | |
| SCHEMBL8208921 | 0.77 | MMP1 (0.67) | MMP1MMP13MMP9 | |
| SCHEMBL6933036 | 0.76 | MMP13 (0.58) | MMP1MMP13MMP9MMP8 | |
| SCHEMBL6928530 | 0.75 | MMP13 (1.00) | MMP1MMP13MMP9 | |
| SCHEMBL6933032 | 0.74 | MMP13 (1.00) | MMP1MMP13MMP9MMP8 | |
| Anisole SCHEMBL27478392 | 0.72 | MMP1 (0.70) | MMP1MMP13MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0970046-A1 | N-HYDROXY-2-(ALKYL, ARYL, OR HETEROARYL SULFANYL, SULFINYL OR SULFONYL)-3-SUBSTITUTED ALKYL, ARYL OR HETEROARYLAMIDES AS MATRIX METALLOPROTEINASE INHIBITORS | American Cyanamid Company (US) | 2000-01-12 | — | — | EP | disclosed |
| WO-1998038163-A1 | N-HYDROXY-2-(ALKYL, ARYL, OR HETEROARYL SULFANYL, SULFINYL OR SULFONYL)-3-SUBSTITUTED ALKYL, ARYL OR HETEROARYLAMIDES AS MATRIX METALLOPROTEINASE INHIBITORS | AMERICAN CYANAMID COMPANY (US) | 1998-09-03 | — | — | WO | disclosed |