Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.46 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 2/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7359072 | 0.91 | KDM4E (0.52) | KDM4EHDAC1POLBTBXA2RDRD2 | |
| SCHEMBL29129962 | 0.79 | ALDH1A1 (0.52) | KDM4EHDAC1HDAC8POLBALDH1A1 | |
| SCHEMBL7358797 | 0.77 | KDM4E (0.59) | KDM4EHDAC1HDAC8POLBTBXA2R | |
| SCHEMBL945578 | 0.75 | POLB (0.61) | POLBHTTAGTR1AGTR2PPARG | |
| SCHEMBL19156191 | 0.74 | POLB (0.60) | POLBTBXA2RALDH1A1HTTDRD2 | |
| SCHEMBL2171116 | 0.74 | HDAC6 (0.48) | KDM4EHDAC1HDAC8ALDH1A1 | |
| SCHEMBL617824 | 0.73 | TNF (0.68) | KDM4EPOLBALDH1A1HTTPPARG | |
| SCHEMBL17381121 | 0.73 | MEN1 (0.49) | KDM4EHDAC1HDAC8POLBTBXA2R | |
| Hydrochloric Acid SCHEMBL2171109 | 0.73 | HDAC6 (0.47) | KDM4EHDAC1HDAC8ALDH1A1 | |
| SCHEMBL5398566 | 0.72 | KDM4E (0.58) | KDM4EPOLBTBXA2RALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5741804-A | Substituted benzimazoles which inhibit platelet aggrecation | SMITHKLINE BEECHAM CORPORATION (US) | 1998-04-21 | — | — | US | disclosed |
| WO-1994012478-A1 | BENZIMIDAZOLE COMPOUNDS WHICH INHIBIT PLATELET AGGREGATION | SMITHKLINE BEECHAM CORPORATION (US) | 1994-06-09 | — | — | WO | disclosed |