Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | BRD4 | O60885 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.46 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.46 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.46 |
| ▸ | PPARG | P37231 | 4/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7348274 | 0.91 | KDM4E (0.59) | KDM4EHDAC1POLBDRD2TBXA2R | |
| SCHEMBL945578 | 0.75 | POLB (0.61) | POLBAGTR1AGTR2PPARGSMN1; SMN2 | |
| SCHEMBL6484666 | 0.75 | AGTR1 (0.54) | AGTR1AGTR2PPARG | |
| SCHEMBL19156191 | 0.74 | POLB (0.60) | POLBDRD2TBXA2RAGTR1AGTR2 | |
| SCHEMBL615476 | 0.73 | TNF (0.68) | KDM4EBRD4SMN1; SMN2 | |
| SCHEMBL17381121 | 0.73 | MEN1 (0.49) | KDM4EHDAC1POLBDRD2TBXA2R | |
| SCHEMBL7763084 | 0.72 | POLB (0.64) | KDM4EPOLBAGTR1AGTR2PPARG | |
| SCHEMBL8788433 | 0.72 | AGTR1 (0.59) | AGTR1AGTR2PPARG | |
| SCHEMBL8395423 | 0.72 | AGTR1 (0.79) | AGTR1AGTR2PPARG | |
| SCHEMBL10443035 | 0.72 | TLR7 (0.54) | AGTR1AGTR2PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5741804-A | Substituted benzimazoles which inhibit platelet aggrecation | SMITHKLINE BEECHAM CORPORATION (US) | 1998-04-21 | — | — | US | disclosed |
| WO-1994012478-A1 | BENZIMIDAZOLE COMPOUNDS WHICH INHIBIT PLATELET AGGREGATION | SMITHKLINE BEECHAM CORPORATION (US) | 1994-06-09 | — | — | WO | disclosed |