Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.34 |
| ▸ | MME | P08473 | 4/20 | 0.32 |
| ▸ | ACE | P12821 | 3/20 | 0.32 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.31 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.31 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7351455 | 0.84 | SLC6A2 (0.34) | OPRD1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL9197318 | 0.77 | OPRD1 (0.34) | OPRD1SMYD3 | |
| SCHEMBL7346880 | 0.71 | OXER1 (0.36) | OPRD1SLC6A2SLC6A4SMYD3SLC6A3 | |
| SCHEMBL7357794 | 0.69 | CNR2 (0.35) | OPRD1SMYD3CACNA2D1CACNA1BCACNB1 | |
| SCHEMBL26010585 | 0.69 | GAA (0.53) | GAAMAPTMMEACE | |
| SCHEMBL9196790 | 0.69 | CNR2 (0.42) | OPRD1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7328890 | 0.66 | OPRD1 (0.32) | OPRD1CACNA2D1CACNA1BCACNB1 | |
| SCHEMBL27513720 | 0.66 | GAA (0.56) | GAAMAPTOPRD1MMEACE | |
| SCHEMBL28781349 | 0.64 | GAA (0.57) | GAAMAPTMMEACECACNA1B | |
| Hydrochloric Acid SCHEMBL9198794 | 0.64 | SLC6A4 (0.36) | OPRD1SLC6A2SLC6A4SMYD3SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994008965-A1 | N-ALKYLPIPERIDINYL-4-METHYL CARBOXYLIC ESTERS/AMIDES OF CONDENSED RING SYSTEMS AS 5-HT4 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1994-04-28 | — | — | WO | claimed |
| US-5726187-A | N-alkylpiperidinyl-4-methyl carboxylic esters/amides of condensed ring systems as 5-HT4 receptor antagonists | SMITHKLINE BEECHAM PLC (GB) | 1998-03-10 | — | — | US | disclosed |
| WO-1994008965-A1 | N-ALKYLPIPERIDINYL-4-METHYL CARBOXYLIC ESTERS/AMIDES OF CONDENSED RING SYSTEMS AS 5-HT4 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1994-04-28 | — | — | WO | disclosed |