Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | AVPR1A | P37288 | 12/20 | 0.50 |
| ▸ | AVPR2 | P30518 | 11/20 | 0.50 |
| ▸ | AVPR1B | P47901 | 3/20 | 0.49 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.48 |
| ▸ | HTR1A | P08908 | 2/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.48 |
| ▸ | OXTR | P30559 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | HRH1 | P35367 | 1/20 | 0.46 |
| ▸ | GLP1R | P43220 | 1/20 | 0.46 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.46 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7354260 | 0.93 | AVPR1A (0.51) | ALDH1A1AVPR1AAVPR2AVPR1BABCB11 | |
| SCHEMBL7351581 | 0.91 | AVPR2 (0.57) | ALDH1A1AVPR1AAVPR2ABCB11HTR1A | |
| SCHEMBL7353295 | 0.91 | AVPR1A (0.49) | ALDH1A1AVPR1AAVPR2AVPR1BABCB11 | |
| SCHEMBL7349131 | 0.89 | ALDH1A1 (0.56) | ALDH1A1AVPR1AAVPR2AVPR1BABCB11 | |
| SCHEMBL7352193 | 0.88 | AVPR1A (0.62) | ALDH1A1AVPR1AAVPR2AVPR1BABCB11 | |
| SCHEMBL7356694 | 0.85 | AVPR2 (0.55) | AVPR1AAVPR2ABCB11HTR1ACHRM1 | |
| SCHEMBL7356611 | 0.85 | AVPR2 (0.63) | AVPR1AAVPR2ABCB11HTR1ACHRM1 | |
| SCHEMBL7353539 | 0.84 | SPTLC2 (0.59) | ALDH1A1AVPR1AAVPR2AVPR1BABCB11 | |
| SCHEMBL7356074 | 0.83 | AVPR2 (0.55) | ALDH1A1AVPR1AAVPR2ABCB11HTR1A | |
| SCHEMBL7352847 | 0.82 | AVPR2 (0.59) | AVPR1AAVPR2ABCB11HTR1ACHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994001113-A1 | OXYTOCIN ANTAGONIST | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1994-01-20 | — | — | WO | disclosed |
| EP-0114273-A1 | New pharmacologically active pyrazolopyridines | GRUPPO LEPETIT S.p.A. (IT) | 1984-08-01 | — | — | EP | disclosed |