Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 5/20 | 0.53 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7355874 | 0.93 | CD274 (0.54) | F2CD274KDM4EALDH1A1MAPT | |
| SCHEMBL7452057 | 0.92 | HRH3 (0.54) | F2CD274KDM4EALDH1A1MAPT | |
| SCHEMBL7447052 | 0.90 | CD274 (0.55) | F2CD274KDM4EALDH1A1MAPT | |
| SCHEMBL7442536 | 0.86 | CD274 (0.49) | F2CD274KDM4EALDH1A1MEN1 | |
| SCHEMBL7353107 | 0.86 | HRH3 (0.48) | F2CD274MEN1KMT2AHRH3 | |
| SCHEMBL6172550 | 0.84 | F2 (0.76) | F2CD274KDM4EALDH1A1MAPT | |
| SCHEMBL7349015 | 0.83 | CD274 (0.47) | F2CD274KDM4EALDH1A1MEN1 | |
| SCHEMBL6965070 | 0.80 | LTA4H (0.53) | F2KDM4EALDH1A1HRH3 | |
| SCHEMBL7438768 | 0.79 | F2 (0.71) | F2CD274 | |
| SCHEMBL7352515 | 0.79 | S1PR1 (0.53) | F2CD274HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0973517-A4 | ANTITHROMBOTIC AGENTS | LILLY CO ELI (US) | 2002-07-24 | — | — | EP | disclosed |
| EP-0973517-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 2000-01-26 | — | — | EP | disclosed |
| WO-1998048794-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 1998-11-05 | — | — | WO | disclosed |