Barbital

Barbital

SCHEMBL7348703

CCC1(CC)C(=O)NC(=O)NC1=O.CCCC

nearest known ligand 0.90

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.90
ALDH1A1 P00352 4/20 0.47
KDM4E B2RXH2 1/20 0.47
CYP3A4 P08684 1/20 0.47
GABRB3 P28472 1/20 0.47
OPRD1 P41143 1/20 0.47
GABRA2 P47869 1/20 0.47
GABRB2 P47870 1/20 0.47
TP53 P04637 1/20 0.43
MMP9 P14780 7/20 0.42
MMP2 P08253 6/20 0.42
MMP8 P22894 4/20 0.42
MMP13 P45452 4/20 0.42
HSD17B10 Q99714 2/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
MMP3 P08254 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Barbital SCHEMBL8746543 0.97 LMNA (0.85) LMNAALDH1A1KDM4ECYP3A4GABRB3
Barbital SCHEMBL3859278 0.95 LMNA (1.00) LMNAALDH1A1KDM4ECYP3A4GABRB3
Barbital SCHEMBL43818 0.95 LMNA (1.00) LMNAALDH1A1KDM4ECYP3A4GABRB3
Barbital SCHEMBL7592317 0.92 LMNA (0.94) LMNAALDH1A1KDM4ECYP3A4GABRB3
Barbital SCHEMBL21084914 0.92 LMNA (0.94) LMNAALDH1A1KDM4ECYP3A4GABRB3
Barbital SCHEMBL23533431 0.92 LMNA (0.94) LMNAALDH1A1KDM4ECYP3A4GABRB3
Barbital SCHEMBL11328256 0.92 LMNA (0.94) LMNAALDH1A1KDM4ECYP3A4GABRB3
Barbital SCHEMBL21084955 0.92 LMNA (0.94) LMNAALDH1A1KDM4ECYP3A4GABRB3
Barbital SCHEMBL2128102 0.92 LMNA (0.94) LMNAALDH1A1KDM4ECYP3A4GABRB3
Barbital SCHEMBL11328233 0.92 LMNA (0.94) LMNAALDH1A1KDM4ECYP3A4GABRB3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024075720-A1 RESIST UNDERLAYER FILM FORMING COMPOSITION 日産化学株式会社 2024-04-11 WO disclosed
WO-2023145703-A1 COMPOSITION FOR FORMING RESIST UNDERLAYER FILM INCLUDING TERMINAL-BLOCKING POLYMER 日産化学株式会社 2023-08-03 WO disclosed
EP-0398388-B1 Electrophoresis film support FUJI PHOTO FILM CO LTD (JP) 1997-01-08 EP disclosed
US-5068019-A Analysis of proteins with polymer membrane sheets with hydroxypropyl cellulose, triphenyl phosphate, tricresyl phosphate and mixtures FUJI PHOTO FILM CO., LTD. (JP) 1991-11-26 US disclosed
EP-0398388-A1 Electrophoresis film support FUJI PHOTO FILM CO., LTD. (JP) 1990-11-22 EP disclosed
US-4564617-A VASODILATORS, ANALGESICS EISAI CO., LTD. (JP) 1986-01-14 US disclosed
US-4426383-A VASODILATION, ANALGESICS, CNS STIMULANTS, ANTIHISTAMINES EISAI CO., LTD. (JP) 1984-01-17 US disclosed