Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCAT2 | O15382 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 3/20 | 0.39 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | BRAF | P15056 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.36 |
| ▸ | MAPK7 | Q13164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14516696 | 0.83 | KCNQ3 (0.47) | NPC1RAB9AHSPA5GRM4KMT2A | |
| SCHEMBL18027794 | 0.80 | RAB9A (0.59) | NPC1RAB9ANAMPTLMNABRAF | |
| SCHEMBL7444006 | 0.79 | RAB9A (0.50) | NPC1RAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL15771675 | 0.77 | XPO1 (0.41) | NPC1RAB9AHSPA5GRM4HDAC1 | |
| SCHEMBL18993439 | 0.77 | BRAF (0.43) | NPC1RAB9AHSPA5GRM4KMT2A | |
| SCHEMBL6908256 | 0.76 | CHRNB2 (0.49) | NPC1RAB9AHSPA5NAMPTGRM4 | |
| SCHEMBL5202785 | 0.74 | — | — | |
| SCHEMBL7350086 | 0.73 | MALT1 (0.45) | NPC1RAB9AHSPA5LMNA | |
| SCHEMBL7345038 | 0.73 | HSPA5 (0.36) | NPC1RAB9AHSPA5GRM4KMT2A | |
| SCHEMBL16692700 | 0.73 | BRAF (0.41) | NPC1RAB9AGRM4KMT2ABRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5318975-A | 5-pyrimdineamine derivatives | BERLEX LABORATORIES, INC. (US) | 1994-06-07 | — | — | US | disclosed |