Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR3 | P46089 | 2/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 8/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA5A | P35218 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 7/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tetraphenylphosphonium SCHEMBL21957774 | 0.82 | GPR3 (0.50) | GPR3PTPN1ACHECA1CA2 | |
| Trifluoromethanesulfonic Acid SCHEMBL14834168 | 0.76 | GPR3 (0.44) | GPR3PTPN1ACHECA1CA2 | |
| Trifluoromethanesulfonic Acid SCHEMBL4457250 | 0.74 | GPR3 (0.43) | GPR3PTPN1ACHECA1CA2 | |
| Bromide SCHEMBL3314842 | 0.73 | HIF1A (0.41) | — | |
| Trifluoromethanesulfonic Acid SCHEMBL7749104 | 0.73 | GPR3 (0.42) | GPR3PTPN1 | |
| Trifluoromethanesulfonic Acid SCHEMBL6923668 | 0.73 | GPR3 (0.53) | GPR3PTPN1ACHECA1CA2 | |
| Trifluoromethanesulfonic Acid SCHEMBL8088040 | 0.73 | GPR3 (0.53) | GPR3PTPN1ACHECA1CA2 | |
| Biphenyl SCHEMBL31361248 | 0.73 | PTPN1 (0.56) | GPR3PTPN1CA1CA2CA5A | |
| Trifluoromethanesulfonic Acid SCHEMBL6560666 | 0.71 | GPR3 (0.57) | GPR3PTPN1ACHECA1CA2 | |
| Trifluoromethanesulfonic Acid SCHEMBL9618033 | 0.71 | GPR3 (0.52) | GPR3PTPN1ACHECA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080031848-A1 | Preparation of Polymer Conjugates of Therapeutic, Agricultural, and Food Additive Compounds | ELAN PHARMACEUTICALS, INC. | 2008-02-07 | — | — | US | claimed |
| US-12084456-B2 | Isocarbostyril alkaloids and functionalization thereof | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2024-09-10 | — | — | US | disclosed |
| US-20220251071-A1 | METHOD TO MAKE SMALL-MOLECULE MURINE DOUBLE MINUTE 2 PROTEIN (MDM2)-DEGRADING COMPOUNDS, COMPOUNDS FORMED THEREBY, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2022-08-11 | — | — | US | disclosed |
| US-20220064176-A1 | ISOCARBOSTYRIL ALKALOIDS AND FUNCTIONALIZATION THEREOF | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2022-03-03 | — | — | US | disclosed |
| US-8138272-B2 | Preparation of polymer conjugates of therapeutic, agricultural, and food additive compounds | ELAN PHARMACEUTICALS, INC. (US) | 2012-03-20 | — | — | US | disclosed |
| US-20080031848-A1 | Preparation of Polymer Conjugates of Therapeutic, Agricultural, and Food Additive Compounds | ELAN PHARMACEUTICALS, INC. | 2008-02-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080031848-A1 | Preparation of Polymer Conjugates of Therapeutic, Agricultural, and Food Additive Compounds | PIGO, MANBA, OAT | GPR3 4129/4885PTPN1 4579/4885ACHE 398/4885 |
| US-20220064176-A1 | ISOCARBOSTYRIL ALKALOIDS AND FUNCTIONALIZATION THEREOF | NISCH, CIAPIN1, CA7 | GPR3 4062/4885PTPN1 4686/4885ACHE 286/4885 |
| US-12084456-B2 | Isocarbostyril alkaloids and functionalization thereof | NISCH, CIAPIN1, CA7 | GPR3 4062/4885PTPN1 4686/4885ACHE 286/4885 |
| US-20220251071-A1 | METHOD TO MAKE SMALL-MOLECULE MURINE DOUBLE MINUTE 2 PROTEIN (MDM2)-DEGRADING COMPOUNDS, COMPOUNDS FORMED THEREBY, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | MDM2, TP53, MYCBP2 | GPR3 4669/4885PTPN1 3590/4885ACHE 4586/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.