Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 6/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | ESR1 | P03372 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6860628 | 0.77 | TSHR (0.49) | KMT2AMEN1TSHRTDP1L3MBTL1 | |
| SCHEMBL7350807 | 0.77 | GRM6 (0.36) | TSHRTDP1ALDH1A1HSD17B10LMNA | |
| SCHEMBL7354139 | 0.76 | TSHR (0.55) | KMT2AMEN1TSHRTDP1L3MBTL1 | |
| SCHEMBL4627338 | 0.75 | TSHR (0.47) | KMT2AMEN1TSHRTDP1L3MBTL1 | |
| SCHEMBL4625869 | 0.75 | TSHR (0.47) | KMT2AMEN1TSHRTDP1L3MBTL1 | |
| SCHEMBL27661910 | 0.74 | TSHR (0.51) | KMT2AMEN1TSHRTDP1L3MBTL1 | |
| SCHEMBL11300674 | 0.74 | TSHR (0.55) | KMT2AMEN1TSHRTDP1L3MBTL1 | |
| SCHEMBL27300155 | 0.74 | TSHR (0.68) | TSHRTDP1L3MBTL1ALDH1A1ESR1 | |
| SCHEMBL18489476 | 0.73 | TSHR (0.44) | KMT2AMEN1TSHRTDP1L3MBTL1 | |
| SCHEMBL8007082 | 0.73 | ALDH1A1 (0.67) | KMT2AMEN1TSHRTDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0691987-A1 | CYCLIC COMPOUNDS USEFUL AS INHIBITORS OF PLATELET GLYCOPROTEIN IIb/IIIa | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-01-17 | — | — | EP | disclosed |
| WO-1994022910-A1 | CYCLIC COMPOUNDS USEFUL AS INHIBITORS OF PLATELET GLYCOPROTEIN IIb/IIIa | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1994-10-13 | — | — | WO | disclosed |