Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | PTPRC | P08575 | 1/20 | 0.39 |
| ▸ | PTPN13 | Q12923 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7348958 | 0.91 | ITGB3 (0.51) | ALDH1A1HTTMAPTMEN1KMT2A | |
| SCHEMBL7345488 | 0.86 | ITGB3 (0.54) | HTTHPGDMAPTMEN1KMT2A | |
| SCHEMBL7350894 | 0.85 | ALDH1A1 (0.41) | ALDH1A1HTTHPGDMAPTMEN1 | |
| SCHEMBL7349536 | 0.85 | ITGB3 (0.48) | ALDH1A1HTTMAPTMEN1KMT2A | |
| SCHEMBL7352241 | 0.83 | ITGB3 (0.52) | ALDH1A1HTTHPGDMAPTMEN1 | |
| SCHEMBL7357579 | 0.83 | ITGB3 (0.46) | ALDH1A1HTTMAPTMEN1KMT2A | |
| SCHEMBL9558500 | 0.82 | ITGB3 (0.45) | HTTHPGDMAPTKMT2AITGB3 | |
| SCHEMBL7347076 | 0.81 | ITGB3 (0.51) | HTTHPGDMAPTMEN1KMT2A | |
| SCHEMBL7346612 | 0.81 | ITGB3 (0.50) | ALDH1A1HTTMAPTMEN1KMT2A | |
| SCHEMBL7350048 | 0.80 | ITGB3 (0.42) | ALDH1A1HPGDMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5973003-A | TREATMENT OF THROMBOSIS, STROKE, MYOCARDIAL INFARCTION, INFLAMMATION AND ARTERIOSCLEROSIS | G. D. SEARLE & CO. (US) | 1999-10-26 | — | — | US | disclosed |
| US-5625093-A | Substituted β-amino acid derivatives useful as platelet aggregation inhibitors | G. D. SEARLE & CO. (US) | 1997-04-29 | — | — | US | disclosed |
| WO-1996037464-A1 | SUBSTITUTED β-AMINO ACID DERIVATIVES USEFUL AS PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1996-11-28 | — | — | WO | disclosed |
| US-5344957-A | Amidinoiphenyl-substituted | G.D. SEARLE & CO. (US) | 1994-09-06 | — | — | US | disclosed |
| US-5239113-A | Anticoagulants | MONSANTO COMPANY (US) | 1993-08-24 | — | — | US | disclosed |