Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 5/20 | 0.43 |
| ▸ | ACACB | O00763 | 1/20 | 0.42 |
| ▸ | IDH1 | O75874 | 6/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.37 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.36 |
| ▸ | CCNK | O75909 | 1/20 | 0.36 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.36 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7350171 | 0.90 | HRH4 (0.45) | HRH4ACACBIDH1MAPK8CCNK | |
| SCHEMBL7342864 | 0.88 | PARP1 (0.40) | HRH3 | |
| SCHEMBL7367199 | 0.87 | PARP1 (0.38) | HRH3 | |
| SCHEMBL7340536 | 0.86 | OGA (0.45) | HRH4IDH1CXCR4HRH3 | |
| SCHEMBL7344262 | 0.85 | HRH3 (0.40) | HRH4HRH3 | |
| SCHEMBL7348379 | 0.78 | OGA (0.43) | HRH4IDH1HRH3 | |
| SCHEMBL27514045 | 0.77 | HSD11B1 (0.37) | HRH4HRH3 | |
| SCHEMBL7342860 | 0.77 | ALK (0.42) | — | |
| SCHEMBL7367195 | 0.76 | PARP1 (0.38) | — | |
| SCHEMBL7376506 | 0.76 | OGA (0.42) | HRH4IDH1CXCR4HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0891359-A1 | NOVEL OXAZOLIDINE DERIVATIVES, PROCESS FOR THEIR PRODUCTION AND MEDICAMENTS CONTAINING THEM | Roche Diagnostics GmbH (DE) | 1999-01-20 | — | — | EP | disclosed |
| WO-1997036899-A1 | NOVEL OXAZOLIDINE DERIVATIVES, PROCESS FOR THEIR PRODUCTION AND MEDICAMENTS CONTAINING THEM | BOEHRINGER MANNHEIM GMBH (DE) | 1997-10-09 | — | — | WO | disclosed |