Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.36 |
| ▸ | NR2C2 | P49116 | 2/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.36 |
| ▸ | RELA | Q04206 | 2/20 | 0.36 |
| ▸ | TAB1 | Q15750 | 2/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.34 |
| ▸ | JAK2 | O60674 | 11/20 | 0.34 |
| ▸ | JAK1 | P23458 | 10/20 | 0.34 |
| ▸ | TYK2 | P29597 | 10/20 | 0.34 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.34 |
| ▸ | FLT3 | P36888 | 1/20 | 0.34 |
| ▸ | BPTF | Q12830 | 1/20 | 0.33 |
| ▸ | IGF1R | P08069 | 1/20 | 0.33 |
| ▸ | JAK3 | P52333 | 1/20 | 0.33 |
| ▸ | OGA | O60502 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7342864 | 0.95 | PARP1 (0.40) | PARP1NFKB1NR2C2NFKB2RELA | |
| SCHEMBL7367195 | 0.90 | PARP1 (0.38) | PARP1NFKB1NR2C2NFKB2RELA | |
| SCHEMBL7350177 | 0.87 | HRH4 (0.43) | HRH3 | |
| SCHEMBL7340536 | 0.85 | OGA (0.45) | HRH3ALKIGF1ROGA | |
| SCHEMBL7344262 | 0.85 | HRH3 (0.40) | HRH3 | |
| SCHEMBL7342860 | 0.84 | ALK (0.42) | PARP1NFKB1NR2C2NFKB2RELA | |
| SCHEMBL27513701 | 0.82 | ALK (0.42) | PARP1NFKB1NR2C2NFKB2RELA | |
| SCHEMBL7376506 | 0.79 | OGA (0.42) | HRH3ALKIGF1ROGA | |
| SCHEMBL7348379 | 0.78 | OGA (0.43) | HRH3ALKIGF1ROGA | |
| SCHEMBL7344376 | 0.76 | GPR119 (0.37) | PARP1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0891359-A1 | NOVEL OXAZOLIDINE DERIVATIVES, PROCESS FOR THEIR PRODUCTION AND MEDICAMENTS CONTAINING THEM | Roche Diagnostics GmbH (DE) | 1999-01-20 | — | — | EP | disclosed |
| WO-1997036899-A1 | NOVEL OXAZOLIDINE DERIVATIVES, PROCESS FOR THEIR PRODUCTION AND MEDICAMENTS CONTAINING THEM | BOEHRINGER MANNHEIM GMBH (DE) | 1997-10-09 | — | — | WO | disclosed |