Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 14/20 | 0.74 |
| ▸ | ITGA2B | P08514 | 14/20 | 0.74 |
| ▸ | PLA2G2A | P14555 | 3/20 | 0.71 |
| ▸ | PLA2G10 | O15496 | 2/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.42 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.42 |
| ▸ | F10 | P00742 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7355665 | 0.91 | ITGB3 (0.64) | ITGB3ITGA2BPLA2G2APLA2G10PRSS1 | |
| SCHEMBL7381799 | 0.85 | ITGB3 (1.00) | ITGB3ITGA2BPLA2G2A | |
| SCHEMBL7381387 | 0.85 | ITGB3 (0.84) | ITGB3ITGA2BPLA2G2AF10 | |
| SCHEMBL7387468 | 0.85 | ITGB3 (0.84) | ITGB3ITGA2BPLA2G2AF10 | |
| SCHEMBL7389600 | 0.83 | ITGB3 (0.76) | ITGB3ITGA2BPLA2G2A | |
| SCHEMBL7350231 | 0.82 | PLA2G2A (0.68) | ITGB3ITGA2BPLA2G2APLA2G10 | |
| SCHEMBL7378671 | 0.81 | ITGB3 (0.76) | ITGB3ITGA2BPLA2G2APRSS1TMPRSS15 | |
| SCHEMBL7348953 | 0.81 | ITGB3 (0.73) | ITGB3ITGA2BPLA2G2APRSS1TMPRSS15 | |
| SCHEMBL7350092 | 0.80 | ITGB3 (0.69) | ITGB3ITGA2BPLA2G2AF10 | |
| SCHEMBL7349522 | 0.80 | ITGB3 (0.71) | ITGB3ITGA2BPLA2G2APRSS1TMPRSS15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5409939-A | Phenyl amidine thio derivatives useful as platelet aggregation inhibitors | G. D. SEARLE & CO. (US) | 1995-04-25 | — | — | US | claimed |
| WO-1994018162-A1 | PHENYL AMIDINE THIO DERIVATIVES USEFUL AS PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1994-08-18 | — | — | WO | claimed |
| US-5543425-A | ANTIAGGLOMERANTS | G. D. SEARLE & CO. (US) | 1996-08-06 | — | — | US | disclosed |
| US-5409939-A | Phenyl amidine thio derivatives useful as platelet aggregation inhibitors | G. D. SEARLE & CO. (US) | 1995-04-25 | — | — | US | disclosed |
| WO-1994018162-A1 | PHENYL AMIDINE THIO DERIVATIVES USEFUL AS PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1994-08-18 | — | — | WO | disclosed |