Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PELI1 | Q96FA3 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | ERN1 | O75460 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | F7 | P08709 | 2/20 | 0.40 |
| ▸ | F3 | P13726 | 1/20 | 0.40 |
| ▸ | EIF4A1 | P60842 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7357599 | 0.89 | ALDH1A1 (0.42) | PELI1ALDH1A1SMN1; SMN2NPSR1F7 | |
| SCHEMBL7357603 | 0.89 | ALDH1A1 (0.42) | PELI1ALDH1A1SMN1; SMN2NPSR1F7 | |
| SCHEMBL7359628 | 0.82 | PDE4A (0.47) | PELI1ALDH1A1ERN1SMN1; SMN2NPSR1 | |
| SCHEMBL7354395 | 0.79 | PDE4A (0.45) | PELI1ALDH1A1ERN1F7MAPT | |
| SCHEMBL7350348 | 0.79 | PDE4B (0.61) | PELI1ALDH1A1F7F3MAPT | |
| SCHEMBL7441450 | 0.78 | KCNH2 (0.45) | ALDH1A1EIF4A1MAPTAKR1C3AKR1C2 | |
| SCHEMBL7348901 | 0.77 | PDE4A (0.48) | PELI1ERN1F7F3MAPT | |
| SCHEMBL5734991 | 0.76 | ERN1 (0.54) | PELI1ALDH1A1ERN1SMN1; SMN2NPSR1 | |
| SCHEMBL11615026 | 0.75 | ERN1 (0.51) | ERN1 | |
| SCHEMBL7941698 | 0.75 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2EIF4A1MAOAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0834508-B1 | Substituted biphenyl or phenylpyridine derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2001-08-16 | — | — | EP | disclosed |
| US-5877190-A | PHOSPHODIESTERASE INHIBITOR | ADIR ET COMPAGNIE (FR) | 1999-03-02 | — | — | US | disclosed |
| EP-0834508-A1 | Substituted biphenyl or phenylpyridine derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1998-04-08 | — | — | EP | disclosed |