Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLCN2 | P51788 | 2/20 | 0.67 |
| ▸ | CLIC1 | O00299 | 1/20 | 0.67 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.67 |
| ▸ | PTGS2 | P35354 | 14/20 | 0.57 |
| ▸ | METTL3 | Q86U44 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.57 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.57 |
| ▸ | TTR | P02766 | 1/20 | 0.57 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.57 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.57 |
| ▸ | FABP2 | P12104 | 1/20 | 0.57 |
| ▸ | RXRA | P19793 | 1/20 | 0.57 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.57 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.57 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.57 |
| ▸ | PDE4A | P27815 | 1/20 | 0.57 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8352685 | 0.85 | CLCN2 (0.71) | CLCN2CLIC1CXCL8PTGS2METTL3 | |
| SCHEMBL11567302 | 0.84 | CLCN2 (0.77) | CLCN2CLIC1CXCL8PTGS2METTL3 | |
| SCHEMBL20693712 | 0.82 | CLCN2 (0.67) | CLCN2CLIC1CXCL8PTGS2METTL3 | |
| SCHEMBL7347293 | 0.82 | PTGS2 (0.62) | CLCN2CLIC1CXCL8PTGS2MAPK1 | |
| SCHEMBL7165291 | 0.81 | CXCL8 (1.00) | CLCN2CLIC1CXCL8PTGS2METTL3 | |
| SCHEMBL8817745 | 0.80 | CXCL8 (0.97) | CLCN2CLIC1CXCL8PTGS2METTL3 | |
| SCHEMBL11561645 | 0.80 | CLCN2 (0.79) | CLCN2CLIC1CXCL8PTGS2METTL3 | |
| SCHEMBL8817733 | 0.80 | CXCL8 (0.97) | CLCN2CLIC1CXCL8PTGS2METTL3 | |
| SCHEMBL8350978 | 0.79 | CLCN2 (0.62) | CLCN2CLIC1CXCL8PTGS2METTL3 | |
| SCHEMBL8817738 | 0.79 | CLCN2 (0.77) | CLCN2CLIC1CXCL8PTGS2METTL3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5112846-A | Nonsteroidal antiinflammatory agents | WARNER-LAMBERT COMPANY (US) | 1992-05-12 | — | — | US | disclosed |
| US-5075330-A | N-hydroxyamide, N-hydroxythioamide, N-hydroxyurea, and N-hydroxythiourea derivatives of selected NSAIDS as antiinflammatory agents | WARNER-LAMBERT CO. (US) | 1991-12-24 | — | — | US | disclosed |
| US-4981865-A | N-hydroxyamide, N-hydroxythioamide, hydroxyurea, and N-hydroxythiourea derivatives of selected nsaids as antiinflammatory agents | WARNER-LAMBERT CO. (US) | 1991-01-01 | — | — | US | disclosed |