Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | MARK3 | P27448 | 1/20 | 0.36 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.36 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.36 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.36 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.33 |
| ▸ | BUB1 | O43683 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1161439 | 0.84 | L3MBTL1 (0.41) | BCHEL3MBTL1PIM1MARK3MAP4K2 | |
| SCHEMBL28619984 | 0.84 | BCHE (0.39) | BCHEL3MBTL1PIM1MARK3MAP4K2 | |
| SCHEMBL2858266 | 0.83 | HSP90AA1 (0.40) | BCHEL3MBTL1PIM1MARK3MAP4K2 | |
| SCHEMBL15392448 | 0.83 | BCHE (0.38) | BCHEL3MBTL1PIM1MARK3MAP4K2 | |
| SCHEMBL9982679 | 0.81 | L3MBTL1 (0.44) | BCHEL3MBTL1PIM1MARK3MAP4K2 | |
| SCHEMBL1162095 | 0.80 | L3MBTL1 (0.41) | BCHEL3MBTL1PIM1MARK3MAP4K2 | |
| SCHEMBL7346863 | 0.80 | PIM1 (0.37) | BCHEL3MBTL1PIM1MARK3MAP4K2 | |
| SCHEMBL6191341 | 0.79 | L3MBTL1 (0.40) | BCHEL3MBTL1PIM1MARK3MAP4K2 | |
| SCHEMBL7343807 | 0.79 | L3MBTL1 (0.36) | BCHEL3MBTL1PIM1MARK3MAP4K2 | |
| SCHEMBL2860553 | 0.79 | MET (0.40) | BCHEL3MBTL1KDM4EALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5436240-A | Schizophrenia, Parkinson's disease, depression or hypotensive agents using tricyclic amines | THE UPJOHN COMPANY (US) | 1995-07-25 | — | — | US | disclosed |
| WO-1990015058-A1 | HETEROCYCLIC AMINES HAVING CENTRAL NERVOUS SYSTEM ACTIVITY | THE UPJOHN COMPANY (US) | 1990-12-13 | — | — | WO | disclosed |