Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 9/20 | 0.54 |
| ▸ | CTSB | P07858 | 8/20 | 0.54 |
| ▸ | CTSS | P25774 | 4/20 | 0.46 |
| ▸ | REN | P00797 | 1/20 | 0.46 |
| ▸ | CTSK | P43235 | 3/20 | 0.46 |
| ▸ | CTSH | P09668 | 2/20 | 0.46 |
| ▸ | CTSC | P53634 | 1/20 | 0.46 |
| ▸ | TACR2 | P21452 | 4/20 | 0.45 |
| ▸ | TGM2 | P21980 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7351491 | 1.00 | CTSL (0.54) | CTSLCTSBCTSSRENCTSK | |
| SCHEMBL7351482 | 1.00 | CTSL (0.54) | CTSLCTSBCTSSRENCTSK | |
| SCHEMBL7353053 | 0.88 | CTSL (0.72) | CTSLCTSBCTSSCTSKCTSH | |
| SCHEMBL7353049 | 0.88 | CTSL (0.72) | CTSLCTSBCTSSCTSKCTSH | |
| SCHEMBL8492550 | 0.88 | CTSL (0.72) | CTSLCTSBCTSSCTSKCTSH | |
| SCHEMBL7351499 | 0.85 | DPP8 (0.45) | CTSLCTSBRENTGM2 | |
| SCHEMBL7400246 | 0.85 | CTSL (0.73) | CTSLCTSBCTSSCTSKCTSH | |
| SCHEMBL7400251 | 0.85 | CTSL (0.73) | CTSLCTSBCTSSCTSKCTSH | |
| SCHEMBL7400248 | 0.85 | CTSL (0.73) | CTSLCTSBCTSSCTSKCTSH | |
| SCHEMBL7359183 | 0.85 | CTSL (0.61) | CTSLCTSBCTSSCTSKCTSH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6287840-B1 | PEPTIDOMIMETICS; COUPLING, DEBLOCKING; ANTIARTHRITIC, ANTITUMOR, ANTICARCINOGENIC, AND ANTIMETASTASIS AGENTS; MUSCULAR DYSTROPHY, GLOMERULONEPHRITIS, MALARIA, ALZHEIMER*S DISEASE | AXYS PHARMACEUTICALS, INC. | 2001-09-11 | — | — | US | disclosed |
| US-5976858-A | (S)-(E)-3-(4-MORPHOLINE-CARBONYLLEUCYL)AMINO-5-PHENYL-1-PHENYL SULFONYL-1-PENTENE AND OTHERS; ANTIARTHRITIS/ANTITUMOR/ ANTIINFLAMMATORY/ANTIMETASTASIS AGENTS; TREATMENT OF MUSCULAR DYSTROPHY, MALARIA, ALZHEIMER'S AND AUTOIMMUNE DISEASES | ARRIS PHARMACEUTICALS (US) | 1999-11-02 | — | — | US | disclosed |