Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 11/20 | 0.73 |
| ▸ | CTSB | P07858 | 8/20 | 0.73 |
| ▸ | CTSS | P25774 | 4/20 | 0.61 |
| ▸ | CTSK | P43235 | 3/20 | 0.60 |
| ▸ | CTSH | P09668 | 1/20 | 0.60 |
| ▸ | CTSC | P53634 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7400248 | 1.00 | CTSL (0.73) | CTSLCTSBCTSSCTSKCTSH | |
| SCHEMBL7400251 | 1.00 | CTSL (0.73) | CTSLCTSBCTSSCTSKCTSH | |
| SCHEMBL7351491 | 0.85 | CTSL (0.54) | CTSLCTSBCTSSCTSKCTSH | |
| SCHEMBL7351502 | 0.85 | CTSL (0.54) | CTSLCTSBCTSSCTSKCTSH | |
| SCHEMBL7351482 | 0.85 | CTSL (0.54) | CTSLCTSBCTSSCTSKCTSH | |
| SCHEMBL7349448 | 0.84 | CTSL (1.00) | CTSLCTSBCTSSCTSKCTSH | |
| SCHEMBL7355581 | 0.84 | CTSL (1.00) | CTSLCTSBCTSSCTSKCTSH | |
| SCHEMBL7355588 | 0.84 | CTSL (1.00) | CTSLCTSBCTSSCTSKCTSH | |
| SCHEMBL7349443 | 0.84 | CTSL (1.00) | CTSLCTSBCTSSCTSKCTSH | |
| SCHEMBL7349450 | 0.84 | CTSL (1.00) | CTSLCTSBCTSSCTSKCTSH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995023222-A1 | IRREVERSIBLE CYSTEINE PROTEASE INHIBITORS CONTAINING VINYL GROUPS CONJUGATED TO ELECTRON WITHDRAWING GROUPS | KHEPRI PHARMACEUTICALS, INC. (US) | 1995-08-31 | — | — | WO | disclosed |