Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.35 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NPY1R | P25929 | 1/20 | 0.35 |
| ▸ | NPY2R | P49146 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.32 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.31 |
| ▸ | PLK1 | P53350 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7295993 | 0.94 | L3MBTL1 (0.56) | L3MBTL1PLA2G1BPLA2G2ATSHRNPY1R | |
| SCHEMBL7299180 | 0.92 | L3MBTL1 (0.58) | L3MBTL1PLA2G1BPLA2G2ATSHRNPY1R | |
| SCHEMBL7297171 | 0.92 | L3MBTL1 (0.58) | L3MBTL1PLA2G1BPLA2G2ATSHRNPY1R | |
| SCHEMBL8414636 | 0.82 | L3MBTL1 (0.51) | L3MBTL1PLA2G1BPLA2G2ATSHRNPY1R | |
| SCHEMBL24180452 | 0.80 | PLA2G1B (0.55) | L3MBTL1PLA2G1BPLA2G2AGPR84LMNA | |
| SCHEMBL7351997 | 0.80 | L3MBTL1 (0.50) | L3MBTL1PLA2G1BPLA2G2ATSHRNPY1R | |
| SCHEMBL8279073 | 0.78 | PLA2G1B (0.59) | L3MBTL1PLA2G1BPLA2G2AGPR84LMNA | |
| SCHEMBL7296001 | 0.78 | L3MBTL1 (0.53) | L3MBTL1PLA2G1BPLA2G2ATSHRNPY1R | |
| SCHEMBL3533620 | 0.78 | PLA2G1B (0.59) | L3MBTL1PLA2G1BPLA2G2AGPR84LMNA | |
| SCHEMBL3532106 | 0.78 | PLA2G1B (0.59) | L3MBTL1PLA2G1BPLA2G2AGPR84LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5652247-A | VASOPRESSIN ANTAGONIST | OTSUKA PHARMACEUTICAL CO., LTD (JP) | 1997-07-29 | — | — | US | disclosed |
| US-5436254-A | Vaopressin antagonists | OTSUKA PHARMACEUTICAL COMPANY, LTD. (JP) | 1995-07-25 | — | — | US | disclosed |
| CN-1091288-A | The oxytocin antagonist | OTSUKA PHARMA CO LTD (JP) | 1994-08-31 | — | — | CN | disclosed |
| EP-0602209-A1 | OXYTOCIN ANTAGONIST | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-06-22 | — | — | EP | disclosed |
| EP-0382185-B1 | Carbostyril derivatives | OTSUKA PHARMA CO LTD (JP) | 1994-06-15 | — | — | EP | disclosed |
| WO-1994001113-A1 | OXYTOCIN ANTAGONIST | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1994-01-20 | — | — | WO | disclosed |
| US-5225402-A | Vasopressin antagonist, vasodilation, hypotensive, diuretics and anticoagulants | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1993-07-06 | — | — | US | disclosed |