Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | PLA2G1B | P04054 | 3/20 | 0.36 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NPY1R | P25929 | 1/20 | 0.36 |
| ▸ | NPY2R | P49146 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | PSMD14 | O00487 | 2/20 | 0.32 |
| ▸ | MMP2 | P08253 | 2/20 | 0.32 |
| ▸ | ATG4B | Q9Y4P1 | 2/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | RAD52 | P43351 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7296001 | 0.93 | L3MBTL1 (0.53) | L3MBTL1PLA2G1BPLA2G2ATSHRNPY1R | |
| SCHEMBL7297180 | 0.91 | L3MBTL1 (0.56) | L3MBTL1PLA2G1BPLA2G2ATSHRNPY1R | |
| SCHEMBL7299184 | 0.91 | L3MBTL1 (0.56) | L3MBTL1PLA2G1BPLA2G2ATSHRNPY1R | |
| SCHEMBL11847918 | 0.86 | L3MBTL1 (0.44) | L3MBTL1PLA2G1BPLA2G2ATSHRNPY1R | |
| SCHEMBL8414636 | 0.84 | L3MBTL1 (0.51) | L3MBTL1PLA2G1BPLA2G2ATSHRNPY1R | |
| SCHEMBL24180452 | 0.82 | PLA2G1B (0.55) | L3MBTL1PLA2G1BPLA2G2ALMNAPSMD14 | |
| SCHEMBL11396006 | 0.81 | THRB (0.43) | L3MBTL1PLA2G1BPLA2G2ATSHRNPY1R | |
| SCHEMBL3533620 | 0.80 | PLA2G1B (0.59) | L3MBTL1PLA2G1BPLA2G2ALMNAPSMD14 | |
| SCHEMBL8279073 | 0.80 | PLA2G1B (0.59) | L3MBTL1PLA2G1BPLA2G2ALMNAPSMD14 | |
| SCHEMBL3532106 | 0.80 | PLA2G1B (0.59) | L3MBTL1PLA2G1BPLA2G2ALMNAPSMD14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5652247-A | VASOPRESSIN ANTAGONIST | OTSUKA PHARMACEUTICAL CO., LTD (JP) | 1997-07-29 | — | — | US | disclosed |
| US-5436254-A | Vaopressin antagonists | OTSUKA PHARMACEUTICAL COMPANY, LTD. (JP) | 1995-07-25 | — | — | US | disclosed |
| EP-0602209-A1 | OXYTOCIN ANTAGONIST | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-06-22 | — | — | EP | disclosed |
| EP-0382185-B1 | Carbostyril derivatives | OTSUKA PHARMA CO LTD (JP) | 1994-06-15 | — | — | EP | disclosed |
| WO-1994001113-A1 | OXYTOCIN ANTAGONIST | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1994-01-20 | — | — | WO | disclosed |
| US-5225402-A | Vasopressin antagonist, vasodilation, hypotensive, diuretics and anticoagulants | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1993-07-06 | — | — | US | disclosed |