⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7361258 | 0.67 | RAB9A (0.31) | — | |
| SCHEMBL9591692 | 0.52 | TSHR (0.55) | — | |
| SCHEMBL9591701 | 0.52 | TSHR (0.55) | — | |
| SCHEMBL21408644 | 0.52 | DGKA (0.41) | — | |
| SCHEMBL21408651 | 0.52 | DGKA (0.41) | — | |
| SCHEMBL11858057 | 0.52 | DGKA (0.59) | — | |
| SCHEMBL11851677 | 0.52 | DGKA (0.59) | — | |
| SCHEMBL11851395 | 0.52 | DGKA (0.59) | — | |
| SCHEMBL11859182 | 0.52 | DGKA (0.59) | — | |
| SCHEMBL5607081 | 0.51 | TSHR (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0372484-B1 | Condensed benzene derivative | ZERIA PHARM CO LTD (JP) | 1994-10-26 | — | — | EP | disclosed |
| US-5028604-A | Cognition Activators | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1991-07-02 | — | — | US | disclosed |
| EP-0372484-A2 | Condensed benzene derivative | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1990-06-13 | — | — | EP | disclosed |