Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.42 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.42 |
| ▸ | XBP1 | P17861 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MPO | P05164 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7354294 | 0.92 | KMT2A (0.44) | CHRM2LMNAMITFCNR1CNR2 | |
| SCHEMBL7352479 | 0.77 | CYP3A4 (0.37) | NPSR1L3MBTL1KDM4ECYP2D6 | |
| SCHEMBL7351671 | 0.77 | APLNR (0.36) | KMT2A | |
| SCHEMBL7345491 | 0.76 | MEN1 (0.44) | CHRM2LMNAMITFCNR1CNR2 | |
| SCHEMBL1343815 | 0.74 | APLNR (0.36) | — | |
| SCHEMBL7351720 | 0.73 | KMT2A (0.41) | CHRM2LMNAHTTKDM4EALDH1A1 | |
| SCHEMBL1345953 | 0.72 | ADRA2C (0.46) | LMNANPSR1L3MBTL1KDM4ECYP2D6 | |
| SCHEMBL31573345 | 0.72 | APLNR (0.39) | CYP2D6KMT2A | |
| SCHEMBL21767384 | 0.71 | APLNR (0.37) | — | |
| SCHEMBL7354606 | 0.71 | MEN1 (0.60) | CHRM2LMNAMITFCNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0972764-A1 | Aminoalcohols and aminoketones as CNS active agents | Universita Degli Studi di Firenze (IT) | 2000-01-19 | — | — | EP | claimed |
| EP-0972764-A1 | Aminoalcohols and aminoketones as CNS active agents | Universita Degli Studi di Firenze (IT) | 2000-01-19 | — | — | EP | disclosed |