⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3059429 | 0.87 | — | — | |
| Hydrochloric Acid SCHEMBL29010691 | 0.83 | — | — | |
| SCHEMBL289810 | 0.83 | — | — | |
| Hydrochloric Acid SCHEMBL30866158 | 0.79 | ALDH1A1 (0.31) | — | |
| SCHEMBL2233938 | 0.79 | GABRR1 (0.30) | — | |
| SCHEMBL10937040 | 0.79 | GABRR1 (0.30) | — | |
| SCHEMBL11379748 | 0.78 | — | — | |
| SCHEMBL23004092 | 0.73 | ALDH1A1 (0.33) | — | |
| SCHEMBL15167043 | 0.73 | — | — | |
| SCHEMBL4536095 | 0.73 | ENPEP (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8138227-B2 | Method for inhibiting or reversing non-enzymatic glycation | TRUSTEES OF DARTMOUTH COLLEGE (US) | 2012-03-20 | — | — | US | disclosed |
| US-20080009547-A1 | Method for inhibiting or reversing non-enzymatic glycation | TRUSTEES OF DARTMOUTH COLLEGE | 2008-01-10 | — | — | US | disclosed |
| CN-1117585-C | Nisin in combination with glycerol monolaurate having anti-helicobacter activity | AMBI INC (US) | 2003-08-13 | — | — | CN | disclosed |
| CN-1207045-A | Nisin in combination with glycerol monolaurate having anti-helicobacter activity | APPLIED MICROBIOLOGY INC (US) | 1999-02-03 | — | — | CN | disclosed |
| EP-0871469-A1 | NISIN IN COMBINATION WITH GLYCEROL MONOLAURATE ACTIVE AGAINST HELICOBACTER | Ambi, Inc. (US) | 1998-10-21 | — | — | EP | disclosed |
| US-5804549-A | Compositions with activity against helicobacter | AMBI INC. (US) | 1998-09-08 | — | — | US | disclosed |
| WO-1997025032-A3 | MONOGLYCERIDE COMPOSITIONS AND THEIR USE AGAINST HELICOBACTER | APPLIED MICROBIOLOGY INC (US) | 1997-11-13 | — | — | WO | disclosed |
| WO-1997036600-A1 | POLYSORBATE-CONTAINING COMPOSITIONS AND THEIR USE AGAINST HELICOBACTER | AMBI INC. (US) | 1997-10-09 | — | — | WO | disclosed |
| WO-1997025055-A9 | NISIN IN COMBINATION WITH GLYCEROL MONOLAURATE ACTIVE AGAINST HELICOBACTER | — | 1997-09-12 | — | — | WO | disclosed |
| WO-1997025055-A1 | NISIN IN COMBINATION WITH GLYCEROL MONOLAURATE ACTIVE AGAINST HELICOBACTER | AMBI INC. (US) | 1997-07-17 | — | — | WO | disclosed |
| WO-1997025032-A2 | MONOGLYCERIDE COMPOSITIONS AND THEIR USE AGAINST HELICOBACTER | AMBI INC. (US) | 1997-07-17 | — | — | WO | disclosed |
| WO-1997025032-A2 | MONOGLYCERIDE COMPOSITIONS AND THEIR USE AGAINST HELICOBACTER | AMBI INC. (US) | 1997-07-17 | — | — | WO | disclosed |