Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR4 | Q13639 | 2/20 | 0.51 |
| ▸ | DRD4 | P21917 | 8/20 | 0.50 |
| ▸ | AGER | Q15109 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 2/20 | 0.46 |
| ▸ | DRD3 | P35462 | 2/20 | 0.46 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.45 |
| ▸ | HTR3B | O95264 | 1/20 | 0.45 |
| ▸ | HTR3A | P46098 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.45 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9021444 | 0.88 | HTR4 (0.66) | HTR4DRD4DRD2 | |
| SCHEMBL7319265 | 0.85 | HTR4 (0.70) | HTR4DRD2HTR3EHTR3BHTR3A | |
| Hydrochloric Acid SCHEMBL7330354 | 0.84 | HTR4 (0.69) | HTR4DRD2HTR3EHTR3BHTR3A | |
| SCHEMBL9021909 | 0.84 | HTR4 (0.72) | HTR4DRD4 | |
| SCHEMBL9022232 | 0.81 | DRD4 (0.55) | HTR4DRD4DRD2 | |
| SCHEMBL11091966 | 0.80 | DRD4 (0.57) | DRD4AGERDRD2DRD3HTR3E | |
| SCHEMBL9645522 | 0.79 | DRD4 (0.53) | HTR4DRD4DRD2DRD3HTR3E | |
| SCHEMBL11196808 | 0.78 | DRD4 (0.49) | DRD4AGERDRD2DRD3 | |
| SCHEMBL11084279 | 0.78 | DRD4 (0.49) | DRD4AGERDRD2DRD3 | |
| SCHEMBL7296558 | 0.78 | HTR4 (0.60) | HTR4DRD4AGER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0566609-A1 | AZABICYDIC AND AZATRICYDIC DERIVATIVES, PROCESS AND INTERMEDIATES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SMITHKLINE BEECHAM PLC (GB) | 1993-10-27 | — | — | EP | disclosed |
| WO-1992012149-A1 | AZABICYDIC AND AZATRICYDIC DERIVATIVES, PROCESS AND INTERMEDIATES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SMITHKLINE BEECHAM PLC (GB) | 1992-07-23 | — | — | WO | disclosed |