Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 13/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7347227 | 0.81 | ALDH1A1 (0.52) | ALDH1A1POLBMAPTMEN1KMT2A | |
| SCHEMBL7346638 | 0.77 | ALDH1A1 (0.57) | ALDH1A1POLBMAPTMEN1KMT2A | |
| SCHEMBL7346112 | 0.70 | ALDH1A1 (0.54) | ALDH1A1POLBMAPTMEN1KMT2A | |
| SCHEMBL7353780 | 0.70 | ALDH1A1 (0.47) | ALDH1A1POLBMAPTMEN1KMT2A | |
| SCHEMBL4414411 | 0.69 | ALDH1A1 (0.61) | ALDH1A1POLBMAPTMEN1KMT2A | |
| SCHEMBL10951363 | 0.69 | ALDH1A1 (0.67) | ALDH1A1POLBMAPTMEN1KMT2A | |
| SCHEMBL9636234 | 0.68 | ALDH1A1 (0.58) | ALDH1A1POLBMAPTMEN1KMT2A | |
| SCHEMBL8827915 | 0.68 | POLB (0.74) | ALDH1A1POLBMAPTMEN1KMT2A | |
| SCHEMBL3748699 | 0.68 | ALDH1A1 (0.65) | ALDH1A1POLBMAPTMEN1KMT2A | |
| SCHEMBL8188675 | 0.68 | ALDH1A1 (0.72) | ALDH1A1POLBMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5539123-A | ENZYME INHIBITORS AS ANTIINFLAMMATORY AGENTS, ANTIARTHRITIC AGENTS AND RESPIRATORY SYSTEM DISORDERS | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 1996-07-23 | — | — | US | claimed |