Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7353452 | 0.81 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2NPC1RAB9APOLB | |
| SCHEMBL7346638 | 0.79 | ALDH1A1 (0.57) | ALDH1A1SMN1; SMN2NPC1RAB9APOLB | |
| SCHEMBL10681783 | 0.78 | ALDH1A1 (0.60) | ALDH1A1SMN1; SMN2POLBMEN1KMT2A | |
| SCHEMBL7353780 | 0.78 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2POLBMEN1KMT2A | |
| SCHEMBL11515264 | 0.76 | ALDH1A1 (0.64) | ALDH1A1SMN1; SMN2POLBMEN1KMT2A | |
| SCHEMBL7346653 | 0.75 | ALDH1A1 (0.57) | ALDH1A1SMN1; SMN2NPC1RAB9APOLB | |
| SCHEMBL7346112 | 0.71 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2POLBMEN1KMT2A | |
| SCHEMBL10675268 | 0.71 | HSD11B1 (0.53) | ALDH1A1SMN1; SMN2NPC1RAB9AKMT2A | |
| SCHEMBL16116944 | 0.71 | ALDH1A1 (0.72) | ALDH1A1SMN1; SMN2NPC1RAB9APOLB | |
| SCHEMBL10674370 | 0.70 | HSD11B1 (0.52) | ALDH1A1SMN1; SMN2NPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5539123-A | ENZYME INHIBITORS AS ANTIINFLAMMATORY AGENTS, ANTIARTHRITIC AGENTS AND RESPIRATORY SYSTEM DISORDERS | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 1996-07-23 | — | — | US | claimed |