Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | BTK | Q06187 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KHK | P50053 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7390541 | 0.79 | HRH3 (0.43) | BTKALDH1A1KHKGAA | |
| Hydrochloric Acid SCHEMBL27179039 | 0.77 | BRD4 (0.44) | TP53SMN1; SMN2ALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL27358981 | 0.76 | TP53 (0.49) | TP53SMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL24838133 | 0.76 | TP53 (0.45) | TP53SMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL24837937 | 0.76 | TP53 (0.45) | TP53SMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL19485531 | 0.75 | FPR2 (0.39) | TP53ALDH1A1NPC1RAB9AKHK | |
| SCHEMBL7362650 | 0.75 | GABRP (0.44) | TP53SMN1; SMN2ALDH1A1KHKCHRNB2 | |
| SCHEMBL7362647 | 0.75 | GABRP (0.44) | TP53SMN1; SMN2ALDH1A1KHKCHRNB2 | |
| SCHEMBL7357782 | 0.75 | TP53 (0.44) | TP53SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL5163 | 0.75 | GABRP (0.52) | TP53SMN1; SMN2ALDH1A1CHRNB2CHRNB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995024405-A1 | IMIDAZOLIDIN-2-ONES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND METHOD OF PREPARING THEM | DR. KARL THOMAE GMBH (DE) | 1995-09-14 | — | — | WO | disclosed |