Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINE1 | P05121 | 10/20 | 0.72 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 4/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 4/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.39 |
| ▸ | HTR7 | P34969 | 2/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7354523 | 1.00 | SERPINE1 (0.72) | SERPINE1CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL7359356 | 0.84 | SERPINE1 (0.70) | SERPINE1HTR7KDM4E | |
| SCHEMBL7359365 | 0.84 | SERPINE1 (0.70) | SERPINE1HTR7KDM4E | |
| SCHEMBL7359291 | 0.84 | SERPINE1 (1.00) | SERPINE1HTR7KAT2B | |
| SCHEMBL7359303 | 0.84 | SERPINE1 (1.00) | SERPINE1HTR7KAT2B | |
| SCHEMBL7357820 | 0.82 | SERPINE1 (0.80) | SERPINE1CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL7357832 | 0.82 | SERPINE1 (0.80) | SERPINE1CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL7363228 | 0.82 | SERPINE1 (0.66) | SERPINE1HTR7KAT2B | |
| SCHEMBL7363234 | 0.82 | SERPINE1 (0.66) | SERPINE1HTR7KAT2B | |
| SCHEMBL8806544 | 0.81 | SERPINE1 (0.68) | SERPINE1KAT2BKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995032190-A2 | PHARMACEUTICAL DIKETOPIPERAZINE COMPOUNDS | XENOVA LIMITED (GB) | 1995-11-30 | — | — | WO | claimed |
| US-5750530-A | PLASMINOGEN ACTIVATOR INHIBITORS | XENOVA LIMITED (GB) | 1998-05-12 | — | — | US | disclosed |
| WO-1995032190-A2 | PHARMACEUTICAL DIKETOPIPERAZINE COMPOUNDS | XENOVA LIMITED (GB) | 1995-11-30 | — | — | WO | disclosed |