Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINE1 | P05121 | 9/20 | 0.68 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MPO | P05164 | 2/20 | 0.34 |
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.34 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7362877 | 0.85 | SERPINE1 (0.72) | SERPINE1KAT2B | |
| SCHEMBL7362875 | 0.85 | SERPINE1 (0.72) | SERPINE1KAT2B | |
| SCHEMBL7359303 | 0.81 | SERPINE1 (1.00) | SERPINE1KAT2B | |
| SCHEMBL7359291 | 0.81 | SERPINE1 (1.00) | SERPINE1KAT2B | |
| SCHEMBL7354523 | 0.81 | SERPINE1 (0.72) | SERPINE1KAT2BKDM4E | |
| SCHEMBL7354535 | 0.81 | SERPINE1 (0.72) | SERPINE1KAT2BKDM4E | |
| SCHEMBL7355821 | 0.80 | SERPINE1 (0.64) | SERPINE1GAAMAPTCYP3A4KDM4E | |
| SCHEMBL7355836 | 0.80 | SERPINE1 (0.64) | SERPINE1GAAMAPTCYP3A4KDM4E | |
| SCHEMBL7358028 | 0.79 | SERPINE1 (1.00) | SERPINE1HPGD | |
| SCHEMBL7358033 | 0.79 | SERPINE1 (1.00) | SERPINE1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0799218-A1 | DIARYL-2-(5H)-FURANONES AS COX-2 INHIBITORS | MERCK FROSST CANADA INC. (CA) | 1997-10-08 | — | — | EP | disclosed |